Marianne K Sloss from 11979 Dapple Way, San Diego, CA 92128, age 53

Resumes

Associate Director, Research Project Management

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Location:

San Diego, CA

Industry:

Pharmaceuticals

Work:

Celgene since Aug 2003
Principal Scientist

Education:

University of Nebraska Lincoln 1993 - 1998
PhD, Organic Chemistry

Skills:

Pharmaceutical Industry
Biotechnology
Life Sciences
Drug Discovery
Drug Development
Validation
Oncology
Hplc
Medicinal Chemistry
Drug Design
Organic Chemistry
Chemistry
Organic Synthesis
Lc Ms

Us Patents

Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith
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US Patent:

7723340, May 25, 2010
Filed:

Jan 12, 2006
Appl. No.:

11/332617
Inventors:

Ronald J. Albers - San Diego CA, US
Leticia Ayala - San Carlos CA, US
Steven S. Clareen - San Diego CA, US
Maria Mercedes Delgado Mederos - San Diego CA, US
Robert Hilgraf - San Diego CA, US
Sayee G. Hegde - San Diego CA, US
Kevin Hughes - San Antonio TX, US
Adam Kois - San Diego CA, US
Meg McCarrick - San Diego CA, US
Lisa Nadolny - San Diego CA, US
Moorthy S. S. Palanki - Encinitas CA, US
Kiran Sahasrabudhe - San Diego CA, US
John Sapienza - Chula Vista CA, US
Yoshitaka Satoh - Poway CA, US
Marianne K. Sloss - San Diego CA, US
Elise Sudbeck - San Diego CA, US
Jonathan Wright - San Diego CA, US
Ian Henderson - Hopewell NJ, US
Andrew G. Cole - Robbinsville NJ, US
Assignee:

Signal Pharmaceuticals, LLC - San Diego CA
Pharmacopeia Drug Discovery, Inc. - Cranbury NJ
International Classification:

C07D 473/32
A61K 31/52
A61F 2/82
A61P 3/10
A61P 11/00
C07D 239/50
C07D 239/48
US Classification:

51425216, 51426323, 51426322, 5142632, 5142634, 544277, 544323, 544326, 623 142
Abstract:

Provided herein are Aminopurine Compounds having the following structure:.

Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith
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US Patent:

8101588, Jan 24, 2012
Filed:

Mar 16, 2009
Appl. No.:

12/404413
Inventors:

Ronald J. Albers - San Diego CA, US
Leticia Ayala - San Diego CA, US
Steven S. Clareen - San Diego CA, US
Maria Mercedes Delgado Mederos - San Diego CA, US
Robert Hilgraf - San Diego CA, US
Sayee G. Hegde - San Diego CA, US
Kevin Hughes - San Antonio TX, US
Adam Kois - San Diego CA, US
Meg McCarrick - San Diego CA, US
Lisa Nadolny - San Diego CA, US
Moorthy S. S. Palanki - Encinitas CA, US
Kiran Sahasrabudhe - San Diego CA, US
John Sapienza - Chula Vista CA, US
Yoshitaka Satoh - Poway CA, US
Marianne K. Sloss - San Diego CA, US
Elise Sudbeck - San Diego CA, US
Jonathan Wright - San Diego CA, US
Assignee:

Signal Pharmaceuticals, LLC - San Diego CA
International Classification:

C07D 473/32
C07F 5/02
A61K 31/52
A61K 31/69
A61P 3/10
A61P 11/00
C07D 239/50
C07D 239/48
US Classification:

514 64, 5142342, 514218, 51425216, 5142634, 540575, 544229, 544118, 544277
Abstract:

Provided herein are Aminopurine Compounds having the following structure:.

Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith
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US Patent:

20070060598, Mar 15, 2007
Filed:

Apr 26, 2006
Appl. No.:

11/411413
Inventors:

Ronald Albers - San Diego CA, US
Leticia Ayala - San Diego CA, US
Steven Clareen - San Diego CA, US
Maria Delgado Mederos - San Diego CA, US
Robert Hilgraf - San Diego CA, US
Sayee Hegde - San Diego CA, US
Kevin Hughes - San Antonio TX, US
Adam Kois - San Diego CA, US
Meg McCarrick - San Diego CA, US
Lisa Nadolny - San Diego CA, US
Moorthy Palanki - Encinitas CA, US
Kiran Sahasrabudhe - San Diego CA, US
John Sapienza - Chula Vista CA, US
Yoshitaka Satoh - Poway CA, US
Marianne Sloss - San Diego CA, US
Elise Sudbeck - San Diego CA, US
Jonathan Wright - San Diego CA, US
International Classification:

A61K 31/52
C07D 473/14
US Classification:

514263230, 544277000
Abstract:

Provided herein are Aminopurine Compounds having the following structure: wherein R, Rand Rare as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

Pyrazole Pyrazine Amine Compounds As Kinase Inhibitors, Compositions Thereof And Methods Of Treatment Therewith
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US Patent:

20090270418, Oct 29, 2009
Filed:

Jan 8, 2009
Appl. No.:

12/350722
Inventors:

Marianne Sloss - San Diego CA, US
Jeffrey McKenna - Horsham, GB
Won Hyung Yoon - San Diego CA, US
Stephen Norris - San Diego CA, US
Dale Robinson - Carlsbad CA, US
Jason Parnes - San Diego CA, US
Graziella Shevlin - San Diego CA, US
Paul Erdman - San Diego CA, US
Robert Hilgraf - San Diego CA, US
Ronald Albers - San Diego CA, US
Sayee Hegde - San Diego CA, US
Andrew Wallace - San Diego CA, US
Henry Chan - San Diego CA, US
Loui Madakamutil - San Diego CA, US
Heather Raymon - San Diego CA, US
International Classification:

A61K 31/497
C07D 403/12
A61P 35/00
C12N 9/99
US Classification:

51425505, 544405, 435184
Abstract:

Provided herein are Pyrazole Pyrazine Amine Compounds having the following structure:

Methods Of Treatment Comprising The Administration Of Haloaryl Substituted Aminopurines Or Compositions Thereof
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US Patent:

20090312320, Dec 17, 2009
Filed:

Aug 12, 2009
Appl. No.:

12/540013
Inventors:

Ronald J. Albers - San Diego CA, US
Leticia Ayala - San Carlos CA, US
Steven S. Clareen - San Diego CA, US
Maria Mercedes Delgado Mederos - San Diego CA, US
Robert Hilgraf - San Diego CA, US
Sayee G. Hegde - San Diego CA, US
Kevin Hughes - San Antonio TX, US
Adam Kois - San Diego CA, US
Meg McCarrick - San Diego CA, US
Lisa Nadolny - San Diego CA, US
Moorthy S.S. Palanki - Encinitas CA, US
Kiran Sahasrabudhe - San Mateo CA, US
John Sapienza - Chula Vista CA, US
Yoshitaka Satoh - Poway CA, US
Marianne K. Sloss - San Diego CA, US
Elise Sudbeck - San Diego CA, US
Jonathan Wright - San Diego CA, US
Ian Henderson - Hopewell NJ, US
Andrew G. Cole - Robbinsville NJ, US
International Classification:

A61K 31/52
A61K 31/5377
A61P 29/00
A61P 35/00
A61P 9/00
A61P 25/00
US Classification:

5142342, 5142634, 51426322, 5142632, 51425216
Abstract:

Provided herein are Aminopurine Compounds having the following structure:wherein R, Rand and Rare as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

Substituted Diaminocarboxamide And Diaminocarbonitrile Pyrimidines, Compositions Thereof, And Methods Of Treatment Therewith
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US Patent:

20130029987, Jan 31, 2013
Filed:

Apr 20, 2012
Appl. No.:

13/451574
Inventors:

Brydon L. Bennett - San Diego CA, US
Jan Elsner - San Diego CA, US
Paul Erdman - San Diego CA, US
Robert Hilgraf - San Diego CA, US
Laurie Ann LeBrun - San Diego CA, US
Meg McCarrick - San Diego CA, US
Mehran F. Moghaddam - Carlsbad CA, US
Mark A. Nagy - San Diego CA, US
Stephen Norris - San Diego CA, US
David A. Paisner - Portland OR, US
Marianne Sloss - San Diego CA, US
William J. Romanow - San Diego CA, US
Yoshitaka Satoh - Poway CA, US
Jayashree Tikhe - San Diego CA, US
Won Hyung Yoon - San Diego CA, US
Mercedes Delgado - San Diego CA, US
International Classification:

A61K 31/505
C07D 405/12
C07D 401/12
A61K 31/506
C07D 405/14
C12N 5/071
C07D 413/12
A61K 31/5377
A61P 1/16
A61P 3/10
A61P 3/00
C07D 239/48
C07D 403/12
US Classification:

5142358, 544323, 514275, 544324, 544296, 544122, 544230, 435375
Abstract:

Provided herein are Diaminopyrimidine Compounds having the following structures:

Substituted Diaminocarboxamide And Diaminocarbonitrile Pyrimidines, Compositions Thereof, And Methods Of Treatment Therewith
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US Patent:

20230116093, Apr 13, 2023
Filed:

Mar 29, 2022
Appl. No.:

17/707471
Inventors:

- San Diego CA, US
Mercedes Delgado - San Diego CA, US
Jan Elsner - Solana Beach CA, US
Paul Erdman - San Diego CA, US
Robert Hilgraf - San Diego CA, US
Laurie Ann LeBrun - San Diego CA, US
Meg McCarrick - San Diego CA, US
Mehran F. Moghaddam - Carlsbad CA, US
Mark A. Nagy - Encinitas CA, US
Stephen Norris - San Diego CA, US
David A. Paisner - Portland OR, US
William J. Romanow - San Diego CA, US
Yoshitaka Satoh - Poway CA, US
Marianne Sloss - San Diego CA, US
Jayashree Tikhe - San Diego CA, US
Won Hyung Yoon - San Diego CA, US
International Classification:

C07D 239/48
A61K 31/505
C07D 401/12
C07D 409/12
C07D 403/12
C07D 401/04
C07D 405/12
C07D 239/38
C07D 239/47
Abstract:

Provided herein are Diaminopyrimidine Compounds having the following structures:wherein R, R, R, and Rare as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.

Substituted Aminopurine Compounds, Compositions Thereof, And Methods Of Treatment Therewith
view source
US Patent:

20210128565, May 6, 2021
Filed:

Jan 12, 2021
Appl. No.:

17/147127
Inventors:

- San Diego CA, US
Sogole Bahmanyar - Rancho Santa Fe CA, US
John Frederick Boylan - Bedminster NJ, US
Joshua Hansen - La Jolla CA, US
Dehua Huang - San Diego CA, US
Robert Hubbard - San Diego CA, US
Brandon Jeffy - San Diego CA, US
Jim Leisten - San Marcos CA, US
Mehran Moghaddam - Carlsbad CA, US
Raj K. Raheja - Poway CA, US
Heather Raymon - San Diego CA, US
Kimberly Schwarz - San Diego CA, US
Marianne Sloss - San Diego CA, US
Eduardo Torres - San Diego CA, US
Tam Minh Tran - San Diego CA, US
Shuichan Xu - San Diego CA, US
JingJing Zhao - San Diego CA, US
International Classification:

A61K 31/52
C07D 473/32
A61P 35/00
A61K 31/5377
Abstract:

Provided herein are Aminopurine Compounds having the following structures:

Marianne K Sloss

Marianne Sloss Phones & Addresses

Work

Education

Skills

Industries

Resumes

Associate Director, Research Project Management

Us Patents

Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith

Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith

Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith

Pyrazole Pyrazine Amine Compounds As Kinase Inhibitors, Compositions Thereof And Methods Of Treatment Therewith

Methods Of Treatment Comprising The Administration Of Haloaryl Substituted Aminopurines Or Compositions Thereof

Substituted Diaminocarboxamide And Diaminocarbonitrile Pyrimidines, Compositions Thereof, And Methods Of Treatment Therewith

Substituted Diaminocarboxamide And Diaminocarbonitrile Pyrimidines, Compositions Thereof, And Methods Of Treatment Therewith

Substituted Aminopurine Compounds, Compositions Thereof, And Methods Of Treatment Therewith

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