Mark A Mclaughlin

US Patent:

20090176986, Jul 9, 2009

Filed:

Apr 6, 2007

Appl. No.:

12/226126

Inventors:

Mark McLaughlin - Summit NJ, US
Michael Palucki - Hillsborough NJ, US
Karen Marcantonio - New York NY, US

International Classification:

C07D 471/04

US Classification:

546118

Abstract:

An efficient syntheses for the preparation of the intermediate 2-oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride, and other salt forms of 2-oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine.

US Patent:

20100234603, Sep 16, 2010

Filed:

Mar 12, 2010

Appl. No.:

12/722779

Inventors:

Xin Linghu - Edison NJ, US
Kathleen Linn - North Brunswick NJ, US
Kevin M. Maloney - Piscataway NJ, US
Mark McLaughlin - Summit NJ, US
Gang Qian - Kendall Park NJ, US

International Classification:

C07D 211/14

US Classification:

546194

Abstract:

The present invention relates to novel substituted aryl sulfone intermediates and processes for preparing the same. An aspect of this invention relates to a process for making substituted aryl sulfone intermediates utilizing a one-pot deacylation-carbon/sulfur bond formation step. The invention also relates to a process for preparing intermediates that are used to make the compounds of formula I. Some of the advantages of the present invention include manufacturing flexibility and efficiency, high yield synthesis using a one pot deacylation and carbon-sulfur bond formation step of a thioester intermediate and the like. This and other aspects of the invention will be realized upon review of the specification as a whole.

US Patent:

20100234604, Sep 16, 2010

Filed:

Mar 12, 2010

Appl. No.:

12/722711

Inventors:

Xin Linghu - Edison NJ, US
Kathleen Linn - North Brunswick NJ, US
Kevin M. Maloney - Piscataway NJ, US
Mark McLaughlin - Summit NJ, US
Gang Qian - Kendall Park NJ, US

International Classification:

C07D 211/20
C07D 213/62

US Classification:

546248, 546294

Abstract:

The present invention relates to novel substituted aryl sulfone intermediates and processes for preparing the same. An aspect of this invention relates to a process for making substituted aryl sulfone intermediates utilizing a one-pot deacylation-carbon/sulfur bond formation step. The invention also relates to a process for preparing intermediates that are used to make the compounds of formula I. Some of the advantages of the present invention include manufacturing flexibility and efficiency, high yield synthesis using a one pot deacylation and carbon-sulfur bond formation step of a thioester intermediate and the like. This and other aspects of the invention will be realized upon review of the specification as a whole.

US Patent:

20220281582, Sep 8, 2022

Filed:

Mar 3, 2022

Appl. No.:

17/685961

Inventors:

- Chicago IL, US
Orion P. Watson - Kirkland WA, US
Daniel H. Fletcher - Lake Forest Park WA, US
Ryan A. Fear - Kirkland WA, US
Brent E. Beneke - Mukilteo WA, US
David H. Leibov - Seattle WA, US
Patricia W. Estell - Woodinville WA, US
Norma L. Alvarez-Quinones - Seattle WA, US
Soo H. Teoh - Mill Creek WA, US
Jesse R. Wiseman - Snohomish WA, US
Mark E. Shadell - Seattle WA, US
Mark R. McLaughlin - Snohomish WA, US
Emmett A. Salisbury - Everett WA, US

Assignee:

The Boeing Company - Chicago IL

International Classification:

B64C 1/26
B64F 5/10

Abstract:

An assembly integrates an aft wing spar root fitting to an aircraft fuselage when joining the aircraft wing to the aircraft body. The assembly provides structural strength to the connection between the aircraft wing and the aircraft body, provides corrosion prevention and provides improved inspection capabilities and repair capabilities to the aircraft wing and aircraft body connection.

US Patent:

20220274682, Sep 1, 2022

Filed:

Jan 6, 2022

Appl. No.:

17/570288

Inventors:

- Chicago IL, US
Mark R. McLaughlin - Snohomish WA, US
David H. Leibov - Seattle WA, US

International Classification:

B64C 1/10
B64C 7/00

Abstract:

Embodiments for hybrid pressure deck of an aircraft. One embodiment is a pressure deck disposed over a main gear wheel well of an aircraft. The pressure deck includes longitudinal beams extending in a forward and aft direction between an aft wheel well bulkhead and a rear spar of the aircraft. The pressure deck also includes a web attached to an underside of the longitudinal beams. The web includes a flat web portion supported by transverse stiffeners extending in an inboard and outboard direction, and a curved web portion including arches configured to flex laterally from load in the inboard and outboard direction. A transition between the flat web portion and the curved web portion extends at least partially in the forward and aft direction of the aircraft.

US Patent:

20220234716, Jul 28, 2022

Filed:

Jan 18, 2022

Appl. No.:

17/577863

Inventors:

- Chicago IL, US
Daniel Cox - Seattle WA, US
Steven David Ingham - Everett WA, US
Kyle Alexander Johnson - Everett WA, US
Mark Ronald McLaughlin - Snohomish WA, US
Paul Hungwai Lai - Arcadia CA, US

International Classification:

B64C 1/26
B64C 1/10

Abstract:

A connector to connect a center wing box to a bulkhead of an aircraft. The connector includes a panel with a first edge positioned at the center wing box, an opposing second edge positioned at the bulkhead, and a central section. A first flexible seal extends across the panel and provides for relative movement between the first edge and the central section. A second flexible seal extends across the panel and provides for relative movement between the second edge and the central section.

US Patent:

20210309340, Oct 7, 2021

Filed:

Apr 7, 2020

Appl. No.:

16/841947

Inventors:

- Chicago IL, US
Steven D. Ingham - Everett WA, US
Daniel Cox - Seattle WA, US
Mark R. McLaughlin - Snohomish WA, US
Alfons Menanno - Edmonds WA, US
Soma Gopala Rao Paravata - Bellevue WA, US
Kevin L. Sullivan - Camano Island WA, US

International Classification:

B64C 1/00
B64C 1/06

Abstract:

Embodiments for aircraft pressure deck. One embodiment is a pressure deck of an aircraft. The pressure deck includes beams extending longitudinally along a fuselage of the aircraft, and a web attached to an underside of the beams, the web including arches between adjacent beams to allow the pressure deck to flex laterally. The pressure deck also includes a box structure between a middle pair of the beams and configured to transfer load forward to a rear spar of a wing of the aircraft and aft to an aft wheel well bulkhead of the aircraft. The pressure deck further includes a first intercostal outboard from the box structure and configured to stabilize a first outboard pair of the beams, and a second intercostal outboard from the first intercostal and coupled between a second outboard pair of the beams via a swing link to allow the second intercostal to flex laterally.

US Patent:

20180346429, Dec 6, 2018

Filed:

Nov 18, 2016

Appl. No.:

15/778505

Inventors:

Cheol K. CHUNG - Rahway NJ, US
Guy R. HUMPHREY - Rahway NJ, US
Zhijian LIU - Rahway NJ, US
Mark MCLAUGHLIN - Rahway NJ, US
Yingju XU - Rahway NJ, US
Younong YU - Kenilworth NJ, US
- Rahway NJ, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ

International Classification:

C07D 239/84

Abstract:

Disclosed herein is a novel process for preparing substituted quinazoline compounds of formula (I) using a hydrogen bonding catalyst.