Min Lu - New York NY, US Hong Ji - New York NY, US
Assignee:
Cornell Research Foundation, Inc. - Ithaca NY
International Classification:
A61K 39/21
US Classification:
4241881, 4241921, 4242081, 530300, 530350
Abstract:
The present invention provides polypeptides comprising a stabilized trimer of the carboxyl-terminal core region of the ectodomain of an enveloped virus, such as HIV. A subject polypeptide comprises three monomers that form a trimeric coiled coil in a prefusogenic conformation of an enveloped virus such as HIV. The subject polypeptides are useful as vacciness against enveloped virus, such as HIV, which vaccines are also provided. The present invention also provides methods of vaccinating an individual to prevent or treat HIV infection or prevent or treat infection by another enveloped virus, using a subject vaccine. Antibodies or binding portions thereof raised against a C-terminus trimeric coiled coil motif of an HIV gp41 ectodomain, or carboxyl-terminal core region of the ectodomain of another enveloped virus, are also provided as are methods of making such antibodies. Methods for detecting HIV or other enveloped viruses in a sample, as well as methods of screening for drugs which can inhibit HIV infection or other enveloped virus infection, are also provided by the present invention.
Human Immunodeficiency Virus Envelope Clycoprotein Mutants And Uses Thereof
John Moore - New York NY, US James Binley - San Diego CA, US Min Lu - New York NY, US William Olson - New York NY, US Norbert Schulke - New City NY, US Jason Gardner - Ardsley NY, US Paul Maddon - Scarsdale NY, US Rogier Sanders - Amsterdam, NL
International Classification:
A61K039/21 C07K014/16
US Classification:
424188100, 530395000
Abstract:
This invention provides stable HIV-1 pre-fusion envelope glycoprotein trimeric complexes. This invention also provides related polypeptides and compositions comprising pharmaceutically acceptable particles and the trimeric complexes operably affixed thereto. This invention further provides related nucleic acids, vectors, host cells, compositions, production methods, and prophylactic and therapeutic methods.
The present invention is a method of identifying a compound that has a sufficient level of binding with a target site on a mammalian zinc transporter, or a portion thereof. The method comprises (a) providing a homology model of a mammalian zinc transporter, or portion thereof, comprising at least one target site; and (b) employing computational means to evaluate the level of binding of the compound with the target site, or a portion thereof. If a sufficient level of binding is found, then a compound is identified.
- WILMINGTON DE, US Min Hsun Lu - WILMINGTON DE, US
International Classification:
A47B 47/00 A47B 88/40 A47B 88/90
Abstract:
A multi-compartment storage shelf includes seven connecting boards and inner partitions. The inner partitions each have an engaging groove. At least two of the inner partitions are intersected and interconnected with each other through the engaging grooves of the inner partitions to form a first grid-shaped inner frame. The first grid-shaped inner frame is connected to the first connecting board, the second connecting board, the fourth connecting board, and the fifth connecting board. At least two of the inner partitions are intersected and interconnected with each other through the engaging grooves of the inner partitions to form a second grid-shaped inner frame. The second grid-shaped inner frame is connected to the sixth connecting board and the seventh connecting board, and the third connecting board.
Name / Title
Company / Classification
Phones & Addresses
Min Lu Owner
Impressa Second Hand Stores
530 Craigflower Road, Victoria, BC V9A 2V9 2502940406
Min Lu Medical Officer Int Medical
Food & Drug Administration Administration of Public Health Programs
Jan 2012 to 2000 Freelancing Designer & PhotographerThe Council Of International Students & Organizations
Sep 2011 to 2000 Public Relations Vice ChairThe National Society of Collegiate Scholars (NSCS)
Aug 2011 to 2000 Public Relations RepresentativeUniversity of Miami Miami, FL Apr 2013 to Apr 2013 Samsung Brand AmbassadorUniversity of Miami Miami, FL Jan 2013 to Apr 2013 Mini Cooper Campaign Book - Media Planning TeamAdrienne Arsht Center Miami, FL Sep 2012 to Dec 2012 Design InternshipMedina Brand Media New York, NY May 2012 to Aug 2012 Digital Media InternshipTouching Miami Miami, FL Feb 2012 to May 2012 Advertising InternshipPhilAdthropy Coral Gables, FL Feb 2011 to Feb 2011 Designer & VolunteerNew World Company
Apr 2009 to Jun 2009 Administration Assistant
Education:
University of Miami Coral Gables, FL Jun 2013 Bachelor of Science in Communication
USC Norris Comprehensive Cancer Center 1441 Eastlake Ave, Los Angeles, CA 90089 3238653900 (phone), 3238650061 (fax)
Education:
Medical School Beijing Med Univ, Beijing City, Beijing, China Graduated: 1995
Languages:
Chinese English Spanish
Description:
Dr. Lu graduated from the Beijing Med Univ, Beijing City, Beijing, China in 1995. She works in Los Angeles, CA and specializes in Hematology/Oncology. Dr. Lu is affiliated with Keck Medical Center Of USC and LAC USC Medical Center.
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Bangkok(thailand)
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University of hpa-an
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Work:
Mass Public School - Chinese Teacher
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