Methods and computer software products are provided for predicting nucleic acid hybridization affinity. In one embodiment, hybridization intensity (I) is determined using the equation: where Pi is the value of the ith parameter and Si is a value derived from the sequence of the probe. The methods and software products of the invention may be used for enhancing mutation detection, probe selection and probe array manufacturing quality control.
Nexgen Compliance Solutions, Llc Feb 2016 - Apr 2019
Software Developer
Emoney Advisor Feb 2016 - Apr 2019
Associate Software Engineer
Nexgen Compliance Solutions, Llc Jul 2013 - Feb 2016
Software Test Engineer
Bay Computer Associates May 2012 - Aug 2012
Intern
Wheaton College Jun 2011 - Aug 2011
Ai Researcher
Education:
Wheaton College Massachusetts 2009 - 2013
Bachelors, Bachelor of Arts, Computer Science, Music
Wheaton College (Ma);;2009 – 2013;
Masters, Master of Arts
Skills:
C++ Java C# Vba Linux Asp.net Visual Studio Javascript Windows Python Research Microsoft Word Microsoft Office Powerpoint C Sql Sql Server Management Studio Microsoft Excel Tortoise Svn Wcf Storm Sublime Text Html Cascading Style Sheets Soap Representational State Transfer Resharper Node.js Couchbase Asp.net Mvc Golang Xml
Metis
Data Science Fellow
Netscout Feb 2004 - Nov 2018
Senior Software Developer
Gene Logic 1999 - 2004
Group Leader, Bioinformatics
Education:
University of California, Berkeley 1983 - 1991
Doctorates, Doctor of Philosophy, Physics
Massachusetts Institute of Technology 1979 - 1983
Skills:
Algorithms C++ C Programming Sql Unix Simulation Simulations Distributed Systems Software Engineering Perl Linux Software Design Python Bash Computer Science Wireless Software Development Javascript Statistics Machine Learning Data Mining Keras Data Science Scikit Learn Natural Language Processing
Ellen Word, Betty Scott, Joyce Burke, Edward Rogers, Louise Hilton, Robert Killian, Sue Carson, Bettye Greene, Walter Childs, Shirley Robinson, Maggie Davis
James Reyome (1979-1981), Laura Stimpson (1986-1995), Mark DeWitt (2000-2004), Nathaniel Hunt (1979-1983), Joanna Miller (1966-1969), Jessica Waterman (1990-1992)
Nathan Hunt (1988-1992), Daniel Taylor (1968-1972), Che Vaughters (1990-1994), Micki Cumley (1973-1977), Michelle McHenry (2001-2005), Michael Rylant (1992-1996)