Pamela N Panopoulos

US Patent:

49754653, Dec 4, 1990

Filed:

Mar 28, 1989

Appl. No.:

7/329624

Inventors:

Solomon Motola - Marlton NJ
Annabelle Mogavero - Medford NJ
Gary R. Agisim - Cherry Hill NJ
Pamela N. Panopoulos - Mays Landing NJ

Assignee:

American Home Products Corporation - New York NY

International Classification:

A61K 3119

US Classification:

514557

Abstract:

A liquid water base ibuprofen composition for oral administration is described, the ibuprofen being maintained in suspension by a combination of primary suspending agents and being taste masked by primary taste masking agents, the composition also containing a buffer acid to adjust the pH of the composition to between 1. 5 and up to about 3. 5 and to provide a buffer capacity within the range of 0. 03 to 0. 05 between the initial pH and a pH which is 1. 0 pH unit higher than the initial pH.