Pawanjit Singh Sethi

US Patent:

54097800, Apr 25, 1995

Filed:

Feb 13, 1992

Appl. No.:

7/835625

Inventors:

Wayne Schrier - Cupertino CA
Pawanjit S. Sethi - Livermore CA
Prithipal Singh - Los Altos CA

Assignee:

Chemtrak, Inc. - Sunnyvale CA

International Classification:

B32B 2900

US Classification:

4285375

Abstract:

Systems are provided for the detection of hydrogen peroxide for determination of analytes, where a N-alkylated 3-oxyaniline derivative is covalently bonded to a bibulous support and the other component for forming an indamine dye may be non-covalently bound to the support. Upon passage of a transport medium across the support in the presence of hydrogen peroxide and a peroxidase, an indamine dye is formed. Where a limited amount of hydrogen peroxide is introduced at a site proximal to one end of the support, and the hydrogen peroxide migrates toward the other end, the distance of color development will be related to the amount of hydrogen peroxide, which can be correlated to the amount of analyte in a sample.