Rachel C Buchanan

US Patent:

20190001025, Jan 3, 2019

Filed:

Aug 27, 2018

Appl. No.:

16/113668

Inventors:

- Austin TX, US
Rachel Buchanan - Austin TX, US
Christine Smid - Austin TX, US
Ennio Tasciotti - Houston TX, US

Assignee:

Board of Regents of the University of Texas System - Austin TX

International Classification:

A61L 27/56
A61L 27/38
A61L 27/44
A61L 27/18
A61L 27/20
A61L 27/58
A61L 27/54
A61L 27/16

Abstract:

In some embodiments, the present invention provides compositions that comprise: (1) a biodegradable polymer matrix; and (2) at least one biodegradable reinforcing particle that is dispersed in the matrix. In some embodiments, the biodegradable reinforcing particle is selected from the group consisting of porous oxide particles and porous semiconductor particles. In additional embodiments, the compositions of the present invention further comprise a (3) porogen particle that is also dispersed in the matrix. In further embodiments, the compositions of the present invention are also associated with one or more active agents. In various embodiments, the active agents are associated with the biodegradable polymer matrix, the biodegradable reinforcing particle, and/or the porogen particle. In various embodiments, the compositions of the present invention may be utilized as scaffolds, such as scaffolds for treating bone defects. Further embodiments of the present invention pertain to methods of making the compositions of the present invention.

US Patent:

20180361030, Dec 20, 2018

Filed:

Aug 27, 2018

Appl. No.:

16/113449

Inventors:

- Austin TX, US
Rachel Buchanan - Austin TX, US
Christine Smid - Austin TX, US
Ennio Tasciotti - Houston TX, US

Assignee:

Board of Regents of the University of Texas System - Austin TX

International Classification:

A61L 27/56
A61L 27/18
A61L 27/58
A61L 27/44
A61L 27/38
A61L 27/54
A61L 27/16
A61L 27/20

Abstract:

In some embodiments, the present invention provides compositions that comprise: (1) a biodegradable polymer matrix; and (2) at least one biodegradable reinforcing particle that is dispersed in the matrix. In some embodiments, the biodegradable reinforcing particle is selected from the group consisting of porous oxide particles and porous semiconductor particles. In additional embodiments, the compositions of the present invention further comprise a (3) porogen particle that is also dispersed in the matrix. In further embodiments, the compositions of the present invention are also associated with one or more active agents. In various embodiments, the active agents are associated with the biodegradable polymer matrix, the biodegradable reinforcing particle, and/or the porogen particle. In various embodiments, the compositions of the present invention may be utilized as scaffolds, such as scaffolds for treating bone defects. Further embodiments of the present invention pertain to methods of making the compositions of the present invention.

US Patent:

20170136154, May 18, 2017

Filed:

Sep 20, 2016

Appl. No.:

15/270324

Inventors:

- Austin TX, US
Rachel Buchanan - Austin TX, US
Christine Smid - Austin TX, US
Ennio Tasciotti - Houston TX, US

International Classification:

A61L 27/56
A61L 27/16
A61L 27/44
A61L 27/20
A61L 27/38
A61L 27/54
A61L 27/18

Abstract:

In some embodiments, the present invention provides compositions that comprise: (1) a biodegradable polymer matrix; and (2) at least one biodegradable reinforcing particle that is dispersed in the matrix. In some embodiments, the biodegradable reinforcing particle is selected from the group consisting of porous oxide particles and porous semiconductor particles. In additional embodiments, the compositions of the present invention further comprise a (3) porogen particle that is also dispersed in the matrix. In further embodiments, the compositions of the present invention are also associated with one or more active agents. In various embodiments, the active agents are associated with the biodegradable polymer matrix, the biodegradable reinforcing particle, and/or the porogen particle. In various embodiments, the compositions of the present invention may be utilized as scaffolds, such as scaffolds for treating bone defects. Further embodiments of the present invention pertain to methods of making the compositions of the present invention.