Masahiro Tanaka - San Francisco CA, US Chao Zhang - San Francisco CA, US Kevan Shokat - San Francisco CA, US Alma Burlingame - Sausalito CA, US Kirk Hansen - San Mateo CA, US Raynard Bateman - San Francisco CA, US Stephen DiMagno - Lincoln NE, US
This invention generally relates to pyrazolo pyrimidine derivatives useful as, inter alia, inhibitors of short chain dehydrogenase/reductase (SDR) family of NAD(P)(H) dependent oxido-reductases. More specifically, the invention relates to pyrazolo pyrimidine derivatives, including derivatives and analogs of SDR inhibitors, pharmaceutical compositions containing derivatives and analogs of SDR inhibitors, methods of making derivatives and analogs of SDR inhibitors and methods of use thereof.
Pyrazolo Pyrimidine Derivatives And Methods Of Use Thereof
Masahiro Tanaka - San Francisco CA, US Chao Zhang - San Francisco CA, US Kevan M. Shokat - San Francisco CA, US Alma L. Burlingame - Sausalito CA, US Kirk Hansen - San Mateo CA, US Raynard L. Bateman - San Francisco CA, US Stephen G. DiMagno - Lincoln NE, US
Assignee:
The Regents of the University of California - Oakland CA
This invention generally relates to pyrazolo pyrimidine derivatives useful as, inter alia, inhibitors of short chain dehydrogenase/reductase (SDR) family of NAD(P)(H) dependent oxido-reductases. More specifically, the invention relates to pyrazolo pyrimidine derivatives, including derivatives and analogs of SDR inhibitors, pharmaceutical compositions containing derivatives and analogs of SDR inhibitors, methods of making derivatives and analogs of SDR inhibitors and methods of use thereof.
Pyrazolo Pyrimidine Derivatives And Methods Of Use Thereof
Masahiro Tanaka - San Francisco CA, US Chao Zhang - San Francisco CA, US Kevan M. Shokat - San Francisco CA, US Alma L. Burlingame - Sausalito CA, US Kirk Hansen - San Mateo CA, US Raynard L. Bateman - San Francisco CA, US Stephen G. DiMagno - Lincoln NE, US
Assignee:
The Regents of the University of California - Oakland CA
This invention generally relates to pyrazolo pyrimidine derivatives useful as, inter alia, inhibitors of short chain dehydrogenase/reductase (SDR) family of NAD(P)(H) dependent oxido-reductases. More specifically, the invention relates to pyrazolo pyrimidine derivatives, including derivatives and analogs of SDR inhibitors, pharmaceutical compositions containing derivatives and analogs of SDR inhibitors, methods of making derivatives and analogs of SDR inhibitors and methods of use thereof.
Pyrazolo Pyrimidine Derivatives And Methods Of Use Thereof
- Oakland CA, US Chao Zhang - San Francisco CA, US Kevan M. Shokat - San Francisco CA, US Alma L. Burlingame - Sausalito CA, US Kirk Hansen - San Mateo CA, US Raynard L. Bateman - San Francisco CA, US Stephen G. DiMagno - Lincoln NE, US
International Classification:
C07D 487/04
Abstract:
This invention generally relates to pyrazolo pyrimidine derivatives useful as, inter alia, inhibitors of short chain dehydrogenase/reductase (SDR) family of NAD(P)(H) dependent oxido-reductases. More specifically, the invention relates to pyrazolo pyrimidine derivatives, including derivatives and analogs of SDR inhibitors, pharmaceutical compositions containing derivatives and analogs of SDR inhibitors, methods of making derivatives and analogs of SDR inhibitors and methods of use thereof.
Pyrazolo Pyrimidine Derivatives And Methods Of Use Thereof
- OAKLAND CA, US Chao Zhang - San Francisco CA, US Kevan M. Shokat - San Francisco CA, US Alma L. Burlingame - Sausalito CA, US Kirk Hansen - San Mateo CA, US Raynard L. Bateman - San Francisco CA, US Stephen G. DiMagno - Lincoln NE, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - OAKLAND CA
International Classification:
C07D 487/04
US Classification:
544262, 544280
Abstract:
This invention generally relates to pyrazolo pyrimidine derivatives useful as, inter alia, inhibitors of short chain dehydrogenase/reductase (SDR) family of NAD(P)(H) dependent oxido-reductases. More specifically, the invention relates to pyrazolo pyrimidine derivatives, including derivatives and analogs of SDR inhibitors, pharmaceutical compositions containing derivatives and analogs of SDR inhibitors, methods of making derivatives and analogs of SDR inhibitors and methods of use thereof.
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Raynard Bateman
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