Richard J Caimi
Deceased
from Perkasie, PA
- Also known as:
-
- Rick J Caimi
- Dick J Caimi
- Jr Rick Caimi
- Richard John I
- Phone and address:
-
817 Shadywood Dr, Perkasie, PA 18944
2152570494
Richard Caimi Phones & Addresses
- 817 Shadywood Dr, Perkasie, PA 18944 • 2152570494
- North Cape May, NJ
- Austin, TX
- Sellersville, PA
- 1811 Norristown Rd, Ambler, PA 19002 • 2156530467
- Ithaca, NY
- Montgomery, PA
- 1811 Norristown Rd, Maple Glen, PA 19002
Work
-
Company:GskNov 2016
-
Position:Vice president: biopharm cmc development
Education
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Degree:Doctorates, Doctor of Philosophy
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School / High School:Cornell University1991 to 1995
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Specialities:Biochemistry
Skills
Biopharmaceuticals • Biotechnology • Gmp • Technology Transfer • Cell Culture • Validation • Analytical Chemistry • Fda • Drug Development • Purification • Life Sciences • Pharmaceutical Industry • Biochemistry • Clinical Development • Drug Discovery • Protein Chemistry • Pharmacology • Mass Spectrometry • Formulation • Sop • U.s. Food and Drug Administration • Standard Operating Procedure • Commercialization • Cmc Development
Industries
Biotechnology
Resumes
Vice President: Biopharm Cmc Development
view sourceLocation:
1811 Norristown Rd, Ambler, PA 19002
Industry:
Biotechnology
Work:
Gsk
Vice President: Biopharm Cmc Development
Glaxosmithkline Pharma Gmbh Jan 2015 - Oct 2016
Head Biopharmaceutical External Development and Supply
Gsk Jan 2014 - Dec 2014
Ceos Future Strategy Group
Gsk Feb 2010 - Dec 2013
Director Early Phase Biopharm Cmc Development
Promedior, Inc. Aug 2007 - Jan 2010
Director Analytical and Formulation Development
Vice President: Biopharm Cmc Development
Glaxosmithkline Pharma Gmbh Jan 2015 - Oct 2016
Head Biopharmaceutical External Development and Supply
Gsk Jan 2014 - Dec 2014
Ceos Future Strategy Group
Gsk Feb 2010 - Dec 2013
Director Early Phase Biopharm Cmc Development
Promedior, Inc. Aug 2007 - Jan 2010
Director Analytical and Formulation Development
Education:
Cornell University 1991 - 1995
Doctorates, Doctor of Philosophy, Biochemistry
Doctorates, Doctor of Philosophy, Biochemistry
Skills:
Biopharmaceuticals
Biotechnology
Gmp
Technology Transfer
Cell Culture
Validation
Analytical Chemistry
Fda
Drug Development
Purification
Life Sciences
Pharmaceutical Industry
Biochemistry
Clinical Development
Drug Discovery
Protein Chemistry
Pharmacology
Mass Spectrometry
Formulation
Sop
U.s. Food and Drug Administration
Standard Operating Procedure
Commercialization
Cmc Development
Biotechnology
Gmp
Technology Transfer
Cell Culture
Validation
Analytical Chemistry
Fda
Drug Development
Purification
Life Sciences
Pharmaceutical Industry
Biochemistry
Clinical Development
Drug Discovery
Protein Chemistry
Pharmacology
Mass Spectrometry
Formulation
Sop
U.s. Food and Drug Administration
Standard Operating Procedure
Commercialization
Cmc Development
Us Patents
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Serum Amyloid P Derivatives And Their Preparation And Use
view source -
US Patent:20100317596, Dec 16, 2010
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Filed:Jun 4, 2010
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Appl. No.:12/794132
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Inventors:W. Scott Willett - Doylestown PA, US
Richard J. Caimi - Maple Glen PA, US -
International Classification:A61K 38/14
C07K 9/00
C12P 21/00
C12N 5/10
A61P 37/00 -
US Classification:514 209, 530322, 435 691, 435 681, 435358
-
Abstract:One aspect of the present invention relates to the surprising discovery that modification of a glycan structure on a human SAP polypeptide can increase the biological activity of the SAP polypeptide relative to a corresponding sample of wild-type SAP isolated from human serum. The disclosure provides both variant human SAP polypeptides and methods for making the same. In particular, the present invention provides methods and compositions for in vitro and in vivo addition, deletion, or modification of sugar residues to produce SAP polypeptides, such as a human SAP polypeptide, having a desired glycosylation pattern.
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Pulmonary And Nasal Delivery Of Serum Amyloid P
view source -
US Patent:20130064866, Mar 14, 2013
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Filed:Sep 7, 2012
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Appl. No.:13/607240
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Inventors:W. Scott Willett - Doylestown PA, US
Richard J. Caimi - Maple Glen PA, US
Lynne Anne Murray - King of Prussia PA, US -
Assignee:Promedior, Inc. - Malvern PA
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International Classification:A61K 38/17
A61M 15/00
A61P 11/00
C07K 14/435
A61K 9/14 -
US Classification:424400, 514 212, 530380, 12820312, 12820315
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Abstract:The disclosure relates to methods for delivery of serum amyloid P to the respiratory system. Pharmaceutical compositions comprising SAP suitable for respiratory delivery are also provided.
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Pulmonary And Nasal Delivery Of Serum Amyloid P
view source -
US Patent:20100266643, Oct 21, 2010
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Filed:Apr 1, 2010
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Appl. No.:12/752627
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Inventors:W. Scott Willett - Doylestown PA, US
Richard J. Caimi - Maple Glen PA, US
Lynne Anne Murray - King of Prussia PA, US -
International Classification:A61K 38/16
A61K 9/14
A61P 11/00 -
US Classification:424400, 514 11
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Abstract:The disclosure relates to methods for delivery of serum amyloid P to the respiratory system. Pharmaceutical compositions comprising SAP suitable for respiratory delivery are also provided.
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Serum Amyloid P Derivatives And Their Preparation And Use
view source -
US Patent:20230058309, Feb 23, 2023
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Filed:Mar 15, 2022
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Appl. No.:17/695071
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Inventors:- Lexington MA, US
Richard J. Caimi - Maple Glen PA, US -
International Classification:C07K 14/47
-
Abstract:One aspect of the present invention relates to the surprising discovery that modification of a glycan structure on a human SAP polypeptide can increase the biological activity of the SAP polypeptide relative to a corresponding sample of wild-type SAP isolated from human serum. The disclosure provides both variant human SAP polypeptides and methods for making the same. In particular, the present invention provides methods and compositions for in vitro and in vivo addition, deletion, or modification of sugar residues to produce SAP polypeptides, such as a human SAP polypeptide, having a desired glycosylation pattern.
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Serum Amyloid P Derivatives And Their Preparation And Use
view source -
US Patent:20200369735, Nov 26, 2020
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Filed:Dec 31, 2019
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Appl. No.:16/731320
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Inventors:- Lexington MA, US
Richard J. Caimi - Maple Glen PA, US -
International Classification:C07K 14/47
-
Abstract:One aspect of the present invention relates to the surprising discovery that modification of a glycan structure on a human SAP polypeptide can increase the biological activity of the SAP polypeptide relative to a corresponding sample of wild-type SAP isolated from human serum. The disclosure provides both variant human SAP polypeptides and methods for making the same. In particular, the present invention provides methods and compositions for in vitro and in vivo addition, deletion, or modification of sugar residues to produce SAP polypeptides, such as a human SAP polypeptide, having a desired glycosylation pattern.
-
Serum Amyloid P Derivatives And Their Preparation And Use
view source -
US Patent:20180044387, Feb 15, 2018
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Filed:Apr 20, 2017
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Appl. No.:15/492085
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Inventors:- Lexington MA, US
Richard J. Caimi - Maple Glen PA, US -
International Classification:C07K 14/47
-
Abstract:One aspect of the present invention relates to the surprising discovery that modification of a glycan structure on a human SAP polypeptide can increase the biological activity of the SAP polypeptide relative to a corresponding sample of wild-type SAP isolated from human serum. The disclosure provides both variant human SAP polypeptides and methods for making the same. In particular, the present invention provides methods and compositions for in vitro and in vivo addition, deletion, or modification of sugar residues to produce SAP polypeptides, such as a human SAP polypeptide, having a desired glycosylation pattern.
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