Ruihuan Chen from 30940 Watkins St, Union City, CA 94587, age 61, Phone: 6507390566

Resumes

Chief Executive Officer

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Location:

Palo Alto, CA

Industry:

Pharmaceuticals

Work:

Aluda Pharmaceuticals
Chief Executive Officer
Genentech Dec 2001 - Apr 2015
Associate Scientist
Icahn School of Medicine at Mount Sinai Jun 2001 - Nov 2001
Instructor

Education:

Icahn School of Medicine at Mount Sinai 1997 - 2001
Université Paris Descartes 1993 - 1997
Doctorates, Doctor of Philosophy, Genetics, Medicine Beijing Normal University
Master of Science, Masters, Biochemistry Shanghai Medical College of Fudan University
Bachelors, Bachelor of Science, Pharmacology

Skills:

Cancer
Cell
Animal Models
Pharmaceutical Industry
Antibodies
Patents
Molecular Biology
Biotechnology
Biochemistry

Languages:

English
Mandarin
French

Ruihuan Chen

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Us Patents

Derivative Of Isoindigo, Indigo And Indirubin For The Treatment Of Cancer
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US Patent:

6566341, May 20, 2003
Filed:

Dec 13, 2001
Appl. No.:

10/021589
Inventors:

Longgui Wang - Flushing NY
Xiaomei Liu - Flushing NY
Ruihuan Chen - Foster City CA
Assignee:

Natrogen Therapeutics, Inc. - Whitefish Bay WI
International Classification:

C07D29502
US Classification:

514 25, 536 41
Abstract:

A compound called NATURA, which is a derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and other related Isoindigo, Indigo and Indirubin derivatives are designed such that the bioactivity or bioavailability of the compound is increased. Also, pharmaceutical compositions that include a therapeutically effective amount of at least one of these derivatives and a pharmaceutically acceptable carrier. A method for the use of these pharmaceutical compositions and compounds is taught, wherein a therapeutically effective amount is administered to an animal. The pharmaceutical composition or compound can be re-administered to the animal until a desired treatment or result is accomplished.

Derivatives Of Isoindigo, Indigo And Indirubin And Methods Of Treating Cancer
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US Patent:

6933315, Aug 23, 2005
Filed:

Jun 10, 2004
Appl. No.:

10/864458
Inventors:

Longgui Wang - Flushing NY, US
Xiaomei Liu - Flushing NY, US
Ruihuan Chen - Foster City CA, US
International Classification:

A61K031/404
C07D043/04
US Classification:

514414, 514 25, 536 41, 536 281, 548457
Abstract:

A compound called NATURA, which is a derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and other related Isoindigo, Indigo and Indirubin derivatives are designed such that the bioactivity or bioavailability of the compound is increased. Methods of synthesizing these derivatives is also taught. In addition, pharmaceutical compositions that include a therapeutically effective amount of at least one of these derivatives and a pharmaceutically acceptable carrier. A method for the use of these pharmaceutical compositions and compounds is taught, wherein a therapeutically effective amount is administered to an animal having solid tumor cancer. The pharmaceutical composition or compound can be re-administered to the animal until a desired treatment or result is accomplished.

Antibodies Specific For Tat285-1
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US Patent:

7585953, Sep 8, 2009
Filed:

Sep 13, 2005
Appl. No.:

11/226554
Inventors:

Ruihuan Chen - Foster City CA, US
Heidi S. Phillips - Palo Alto CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US
Assignee:

Genentech, Inc. - South San Francisco CA
International Classification:

C07K 16/00
C12P 21/08
A61K 39/395
C12P 21/04
C07H 21/04
US Classification:

5303879, 4241301, 4241331, 4241411, 4241551, 4241791, 4241811, 4241831, 435 696, 5303871, 5303873, 5303881, 5303888, 5303913, 5303917
Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

Anti-Tat188 Antibodies
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US Patent:

7749504, Jul 6, 2010
Filed:

Apr 11, 2007
Appl. No.:

11/733861
Inventors:

Belinda Cairns - Burlingame CA, US
Ruihuan Chen - Palo Alto CA, US
Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Hartmut Koeppen - Berkeley CA, US
Heidi S. Phillips - Palo Alto CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
Victoria Smith - Burlingame CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US
Assignee:

Genentech, Inc. - South San Francisco CA
International Classification:

A61K 39/395
C12P 21/04
C12P 21/08
C07K 16/00
US Classification:

4241551, 4241331, 4241411, 4241811, 4241831, 435 696, 435 7021, 5303873, 5303879, 5303881, 5303888, 5303917
Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

Antibody Compositions For The Diagnosis And Treatment Of Tumor
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US Patent:

7803915, Sep 28, 2010
Filed:

Sep 8, 2004
Appl. No.:

10/936626
Inventors:

Belinda Cairns - Los Altos CA, US
Ruihuan Chen - Palo Alto CA, US
Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Hartmut Koeppen - Berkeley CA, US
Heidi S. Phillips - Palo Alto CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
Victoria Smith - Burlingame CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US
Chie Sakanaka - San Francisco CA, US
Anan Chuntharapai - Colma CA, US
Chae Janeka Reed - San Francisco CA, US
Assignee:

Genentech, Inc. - South San Francisco CA
International Classification:

C07K 16/00
C12P 21/08
A61K 39/395
C12P 21/04
US Classification:

5303871, 4241301, 4241331, 4241411, 4241551, 4241811, 4241831, 435 696, 435 7021, 5303873, 5303881, 5303888, 5303917
Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

Method Of Treating Inflammatory Arthritis
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US Patent:

7855223, Dec 21, 2010
Filed:

Jul 26, 2006
Appl. No.:

11/494362
Inventors:

Ruihuan Chen - Palo Alto CA, US
Simon K. Mencher - New York NY, US
Allen Tsao - Windlake WI, US
Xiao Mei Liu - Flushing NY, US
Longgui Wang - Flushing NY, US
Assignee:

Natrogen Therapeutics International, Inc. - New York NY
International Classification:

A61K 31/40
A61K 31/405
A61K 31/56
A61K 31/19
US Classification:

514414, 514415, 514416, 514 23, 514159, 514171, 514570, 51425409
Abstract:

The present invention is directed to a method for treating inflammatory arthritis in a mammal. The method typically comprises administering to an animal a therapeutically effective amount of at least one compound selected from indigo, isoindigo, indirubin or derivatives thereof, such as NATURA-α or NATURA. The present invention is further directed to pharmaceutical compositions that include a therapeutically effective amount of at least one compound of the invention, an anti-inflammatory arthritis agent and a pharmaceutically acceptable carrier.

Compositions And Methods For The Diagnosis And Treatment Of Tumor
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US Patent:

8278042, Oct 2, 2012
Filed:

Mar 22, 2010
Appl. No.:

12/661704
Inventors:

Belinda Cairns - Burlingame CA, US
Ruihuan Chen - Foster City CA, US
Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Hartmut Koeppen - Berkeley CA, US
Heidi S. Phillips - Palo Alto CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
Victoria Smith - Burlingame CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US
Assignee:

Genentech, Inc. - South San Francisco CA
International Classification:

C12Q 1/68
US Classification:

435 61
Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

Compositions And Methods For The Diagnosis And Treatment Of Tumor
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US Patent:

20050107595, May 19, 2005
Filed:

Sep 10, 2004
Appl. No.:

10/938061
Inventors:

Belinda Cairns - Burlingame CA, US
Ruihuan Chen - Palo Alto CA, US
Gretchen Frantz - San Francisco CA, US
Kenneth Hillan - San Francisco CA, US
Hartmut Koeppen - Berkeley CA, US
Heidi Phillips - Palo Alto CA, US
Paul Polakis - Burlingame CA, US
Susan Spencer - Tiburon CA, US
Victoria Smith - Burlingame CA, US
P. Williams - Half Moon Bay CA, US
Thomas Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US
Chie Sakanaka - San Francisco CA, US
Anan Chuntharapai - Colma CA, US
Chae Reed - San Francisco CA, US
International Classification:

C07K016/44
C07K016/18
US Classification:

530387300, 530388100
Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.