Shinichi Sakemi

US Patent:

48085901, Feb 28, 1989

Filed:

Jul 15, 1988

Appl. No.:

7/219215

Inventors:

Tatsuo Higa - Okinawa, JP
Shinichi Sakemi - Vero Beach FL
Sue S. Cross - Ft. Pierce FL

Assignee:

Harbor Branch Oceanographic Institution, Inc. - Ft. Pierce FL

International Classification:

A61K 31505
C07D40514

US Classification:

514272

Abstract:

This invention relates to novel compositions which are useful as antitumor, antiviral and antifungal compositions, a process of producing the compositions and a method for inhibiting tumors, viruses and fungi utilizing the composition. More particularly, the novel compositions are derived from marine sponge Theonella sp.

US Patent:

47555297, Jul 5, 1988

Filed:

Jun 26, 1986

Appl. No.:

6/879080

Inventors:

Tatsuo Higa - Okinawa, JP
Shinichi Sakemi - Vero Beach FL

Assignee:

Harbor Branch Oceanographic Institution Inc. - Ft. Pierce FL

International Classification:

A61K 3134
C07D30793

US Classification:

514468

Abstract:

This invention relates to novel guaiazulene compositions which are useful as antitumor, immunomodulatory and antifungal compositions and a process of producing guaiazulene compositions and a method for immunomodulation and inhibiting tumors and fungi utilizing guaiazulene compositions. More particularly, the compositions are derived from marine gorgorian Acalycigorgia, sp.

US Patent:

47313773, Mar 15, 1988

Filed:

Jan 31, 1986

Appl. No.:

6/825061

Inventors:

Tatsuo Higa - Okinawa, JP
Carsten Christophersen - Copenhagen, DK
Shinichi Sakemi - Vero Beach FL

Assignee:

Harbor Branch Oceanographic Institute, Inc. - Ft. Pierce FL

International Classification:

A61K 3135
C07D31902

US Classification:

514452

Abstract:

This invention relates to cyclic peroxide compositions, a process of producing the compositioning and a method for inhibiting tumors utilizing the compositions. More particularly, the compositions are cyclic peroxides which are derived from marine organisms, i. e. , the marine sponge Plakortis lita.