- Pleasanton CA, US Sonhee C. Park - Pleasanton CA, US Ron Flores - San Jose CA, US Christos Kyrou - Goshen NY, US Laurel A. Fisher - Los Angeles CA, US
A method is disclosed for decolorizing a muscadine pomace grape extract by processing the clarified extract by ultrafiltration through a 500-5000 kDa microfiltration membrane to obtain a first permeate in which flavor components are removed. The retentate is subjected to ultrafiltration through a 25-100 kDa ultrafiltration membrane to obtain a second permeate and a second retentate. The polymeric condensed tannins are removed in the second retentate and the second permeate is the decolorized extract having increased levels of polyphenols and lowered levels of sugars and condensed tannins compared to the first retentate. The decolorized extract can be incorporated into skin care compositions, which can also include beta-glucan and grape seed extract. The skin care compositions can and applied to the skin to maintain healthy skin without discoloration. In some embodiments, the compositions are used for reducing inflammation in the skin, including inflammation that results from exposure to ultraviolet radiation. Methods are disclosed for inhibiting the production of anti-inflammatory mediators in skin cells, and inhibiting damage induced by ultraviolet radiation by applying topical compositions which include a decolorized muscadine () pomace solvent extract, beta-glucan and grape seed extract, to the skin.
Muscadine Topical Composition With Low Content Of Condensed Tannin
- Pleasanton CA, US Christos Kyrou - Goshen NY, US Ron Flores - San Jose CA, US Teodoro Ianiro - Concord CA, US Sonhee C. Park - Pleasanton CA, US
Assignee:
Shaklee Corporation - Pleasanton CA
International Classification:
A61K 36/87 A61P 29/00 A61K 9/00
Abstract:
A method for decolorizing a muscadine pomace grape extract by processing the clarified extract by ultrafiltration through a 500-5000 kDa microfiltration membrane to obtain a first permeate in which flavor components are removed. The retentate is subjected to ultrafiltration through a 25-100 kDa ultrafiltration membrane to obtain a second permeate and a second retentate. The polymeric condensed tannins are removed in the second retentate and the second permeate is the decolorized extract having increased levels of polyphenols and lowered levels of sugars and condensed tannins compared to the first retentate. The decolorized extract can be incorporated into skin care compositions, which can also include beta-glucan and grape seed extract. The skin care compositions can and applied to the skin to maintain healthy skin without discoloration, protecting against ultraviolet radiation, and inhibiting the production of anti-inflammatory mediators in skin cells.
Skin care regimens are disclosed, which use five components that each include a composition made with a combination of a decolorized muscadine () pomace solvent extract, beta-glucan and grape seed extract, to improve the appearance of skin. The five components include a toner, day moisturizer, night moisturizer, cleanser and serum. Also disclosed are skin care methods to improve the appearance of skin by the application of effective amounts of these five components.
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