Steven J Rosen

US Patent:

20090082304, Mar 26, 2009

Filed:

Nov 14, 2005

Appl. No.:

11/719121

Inventors:

Kulsoom Ghias - Chicago IL, US
Chunguang Ma - Champaign IL, US
Varsha Gandhi - Houston TX, US
Leonidas C. Platanias - Glencoe IL, US
Nancy L. Krett - Elk Grove Village IL, US
Steven T. Rosen - Evanston IL, US

Assignee:

NORTHWESTERN UNIVERSITY - Evanston IL
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - AUSTIN TX

International Classification:

A61K 31/7076
A61K 31/70
G01N 33/53
C12Q 1/02
C12Q 1/48
C12Q 1/42
C12Q 1/37
A61P 35/00

US Classification:

514 46, 514 43, 436 86, 435 29, 435 15, 435 21, 435 24

Abstract:

The present invention provides methods of treating hematological malignancies, including multi-drug resistant malignancies, with 8-amino-adenosine and variants thereof. Also encompassed by the present invention is a method of predicting the response of a patient diagnosed with a hematological malignancy to treatment with a nucleoside analog and a method of screening candidate drugs for efficacy in treating hematological malignancies.

US Patent:

20120252749, Oct 4, 2012

Filed:

Mar 30, 2012

Appl. No.:

13/435625

Inventors:

Malathy Shanmugam - Lisle IL, US
Samuel K. McBrayer - North Muskegon MI, US
Steven T. Rosen - Evanston IL, US

Assignee:

NORTHWESTERN UNIVERSITY - Evanston IL

International Classification:

A61K 31/704
A61K 31/496
C12Q 1/68
A61P 35/00
C12Q 1/02
G01N 33/574
A61K 31/427
A61K 31/69

US Classification:

514 34, 514365, 51425301, 514 64, 435 29, 435 723, 435 612

Abstract:

Methods of treating cancer comprising administering inhibitors of glucose transporters (GLUTs) are provided. Methods of predicting whether a cancer will respond to treatment with a GLUT inhibitor also are provided.

US Patent:

20130122988, May 16, 2013

Filed:

Nov 14, 2012

Appl. No.:

13/676772

Inventors:

WMS Gaming Inc. - Waukegan IL, US
Jeremy M. Hornik - Chicago IL, US
Joel R. Jaffe - Glenview IL, US
Jeremie D. Moll - Chicago IL, US
Jeffry L. Nauman - Yorkville IL, US
Steven Rosen - Chicago IL, US

Assignee:

WMS Gaming Inc. - Waukegan IL

International Classification:

A63F 13/00

US Classification:

463 20

Abstract:

A gaming system for conducting a wagering game includes at least one input device, at least one display device, and at least one processor. The gaming system further includes at least one memory device that stores a plurality of instructions that, when executed by the at least one processor, cause the at least one processor to operate with the at least one display device and the at least one input device to display a wagering game having an array of symbol positions, the array of symbol positions being populated by a plurality of symbols for indicating a randomly selected outcome, the array of symbol positions forming a plurality of groups of symbol positions, wherein a single reel populates more than one non-adjacent groups of symbol positions.

US Patent:

47799307, Oct 25, 1988

Filed:

Sep 17, 1987

Appl. No.:

7/097833

Inventors:

Steven B. Rosen - Canyon Country CA

International Classification:

A47D 1500

US Classification:

297464

Abstract:

An infant head support for use with infant retaining devices, such as automobile auxiliary seats, infant carriers, swing seats, baby strollers and the like, used for the retention of infants and early age children. The head support comprises a somewhat dense but resilient foam member which is adapted to fit within a pair of opposed side walls on the infant retaining device, e. g. a pair of forwardly extending flange portions on an infant seat. The foam member is formed with a first opening generally sized to conform to and receive the head of an infant. A second opening, which is larger than the first opening, is sized to engage the shoulders and the upper arm portions of the infant. Moreover, the dense but resilient foam member can be captured between the opposed walls on the infant retaining device so that it retains the infant's head in a fixed position. The infant's head creates outwardly projected lateral forces on the foam member which are opposed by the walls of the infant retaining device and thereby retains the infant's head in a position generally aligned with the torso at a point in the life of the infant when the neck muscles are not strong enough to support its head.

US Patent:

D3114716, Oct 23, 1990

Filed:

Jul 16, 1987

Appl. No.:

7/074331

Inventors:

Steven B. Rosen - Saugus CA

US Classification:

D 6601

US Patent:

55493548, Aug 27, 1996

Filed:

Mar 7, 1995

Appl. No.:

8/399823

Inventors:

Steven B. Rosen - Santa Clarita CA

International Classification:

A47C 762

US Classification:

29718413

Abstract:

A reflective seat shield (commonly referred to as a reflective cover) for use in protecting unoccupied infant retaining devices, such as automobile auxiliary seats (e. g. , infant car seats), infant carriers, baby strollers, and the like, from the sun's light and heat. The reflective cover is uniquely designed in such a way as to adaptively fit over a number of different and varying sized and shaped infant retaining devices when in use, and to be compactly folded-up flat or wadded up into a small compact unit for storage when not in use. The reflective cover includes an elastic band or the like along its periphery to retentively hold it closely fitted around and over the infant retaining device. The reflective cover, which is also easily removed from the retaining device allows an attendant to later place a child in the infant receiving seat section of the retaining device which has previously been consistently maintained at a relatively moderate temperature. This protects the child from discomfort and/or injury such as severe burns, etc.

US Patent:

48164020, Mar 28, 1989

Filed:

Jan 7, 1986

Appl. No.:

6/816709

Inventors:

Steven T. Rosen - Chicago IL
James A. Radosevich - Chicago IL
Yixing Ma - Chicago IL

Assignee:

Northwestern University - Evanston IL

International Classification:

G01N 33577
C12N 1500

US Classification:

43524027

Abstract:

Hybridoma HB 8986 produces a murine monoclonal antibody which recognizes a new determinant expressed in bronchopulmonary carcinomas and A549 cell line derived tumors. Immunoperoxidase staining with the hybridoma on formalin fixed, paraffin embedded tissues shows that it specifically stains both the cytoplasmic and cell surface. The monoclonal antibody has the ability to distinguish preferably bronchopulmonary carcinomas with glandular differentiation from other bronchopulmonary carcinomas. Additionally, the monoclonal antibody may identify adenocarcinomas through the body.

US Patent:

20210269803, Sep 2, 2021

Filed:

Jun 17, 2019

Appl. No.:

17/251549

Inventors:

- Duarte CA, US
Piotr Marek Swiderski - San Dimas CA, US
Steven Rosen - Duarte CA, US

International Classification:

C12N 15/117
C12N 15/113
A61K 47/54

Abstract:

Disclosed herein, inter alia, are oligonucleotide-based proteolysis targeting chimeras and methods of use thereof.