Tanja Maria Gruber

age ~58

from Media, PA

Also known as:
  • Tanja M Gruber
  • Tanya M Steger
Phone and address:
140 Victoria Sq, Media, PA 19063
6105662947

Tanja Gruber Phones & Addresses

  • 140 Victoria Sq, Media, PA 19063 • 6105662947
  • 256 Presidential Dr, Wilmington, DE 19807 • 3026581989
  • Greenville, DE
  • 1 Warren Dr, San Francisco, CA 94131 • 4157533665
  • 1657 7Th St, San Francisco, CA 94122 • 4157533665
  • State College, PA
Name / Title
Company / Classification
Phones & Addresses
Tanja Gruber
President
Max and Me Beauty, Ltd
4201 Maple Ave, Oakland, CA 94602

Us Patents

  • Use Of Tetracysteine Tags In Fluorescence-Activated Cell Sorting Analysis Of Prokaryotic Cells Producing Peptides Or Proteins

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  • US Patent:
    7794963, Sep 14, 2010
  • Filed:
    Nov 3, 2008
  • Appl. No.:
    12/263608
  • Inventors:
    Qiong Cheng - Wilmington DE, US
    Kevin Michael Croker - Hockessin DE, US
    Stephen R. Fahnestock - Wilmington DE, US
    Tanja Maria Gruber - Media PA, US
    Kristin Ruebling-Jass - Wilmington DE, US
    Jianzhong Zhang - Wilmington DE, US
  • Assignee:
    E.I. du Pont de Nemours and Company - Wilmington DE
  • International Classification:
    G01N 33/569
    C07K 16/00
  • US Classification:
    435 732, 530329
  • Abstract:
    A process of in vivo labeling and identifying recombinantly produced peptides or proteins within an unpermeabilized prokaryotic host cell. Recombinant prokaryotic cells expressing a fusion peptide comprising at least one tetracysteine tag were labeled in vivo using a biarsenical labeling reagent. A fluorescent activated cell sorter was used to identify and select subpopulations of fluorescent cells wherein the amount of fusion peptide in the cell was proportional to the amount of fluorescence detected.
  • Solubility Tags For The Expression And Purification Of Bioactive Peptides

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  • US Patent:
    7794979, Sep 14, 2010
  • Filed:
    Jan 25, 2010
  • Appl. No.:
    12/692665
  • Inventors:
    Qiong Cheng - Wilmington DE, US
    Linda Jane Decarolis - Wilmington DE, US
    Stephen R. Fahnestock - Wilmington DE, US
    Tanja Maria Gruber - Media PA, US
    Lisa Diane Reiss - Wilmington DE, US
    Pierre E. Rouviere - Wilmington DE, US
  • Assignee:
    E.I. du Pont de Nemours and Company - Wilmington DE
  • International Classification:
    C12P 21/06
    C07H 21/04
  • US Classification:
    435 691, 435 711, 4353201, 4352523, 536 234
  • Abstract:
    Peptide tags, referred to here as inclusion body tags, are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.
  • Recombinant Peptide Production Using A Cross-Linkable Solubility Tag

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  • US Patent:
    7951559, May 31, 2011
  • Filed:
    Jul 14, 2008
  • Appl. No.:
    12/172395
  • Inventors:
    Albert W. Alsop - Wilmington DE, US
    Qiong Cheng - Wilmington DE, US
    Linda Jane Solomon - Wilmington DE, US
    Stephen R. Fahnestock - Wilmington DE, US
    Tanja Maria Gruber - Media PA, US
    Pierre E. Rouviere - Wilmington DE, US
  • Assignee:
    E.I. du Pont de Nemours and Company - Wilmington DE
  • International Classification:
    C07K 14/00
    C12P 21/06
  • US Classification:
    435 691, 530350
  • Abstract:
    The invention relates to the recombinant expression of a peptide of interest in the form of a fusion protein comprising a solubility tag. The fusion protein comprises at least two portions separated by a cleavable peptide sequence wherein one portion is devoid of cysteine residues and the second portion comprises an effective number of cross-linkable cysteine residues. After cell lysis and isolation of the fusion protein, the fusion protein is subsequently cleaved into a mixture of first and second portions. Oxidative cross-linking is used to selectively precipitate one of the two portions to facilitate simple and effective separation of the peptide of interest.
  • Mutant Arabinose Promoter For Inducible Gene Expression

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  • US Patent:
    7998702, Aug 16, 2011
  • Filed:
    Sep 17, 2008
  • Appl. No.:
    12/212271
  • Inventors:
    Tanja Maria Gruber - Media PA, US
    Lisa L. Huang - Hockessin DE, US
  • Assignee:
    E. I. du Pont de Nemours and Company - Wilmington DE
  • International Classification:
    C07H 21/04
    C12N 15/63
    C12N 15/00
    C12P 21/00
  • US Classification:
    435 691, 435 711, 4353201, 536 241
  • Abstract:
    An L-arabinose inducible expression system comprising a mutant arabinose promoter. This system exhibits an increase in heterologous protein production upon induction with L-arabinose and comprises a mutant araB promoter and an AraC transcription binding region. This system retains the tight regulatory control characteristic of the wild type arabinose operon.
  • Peptide Compositions For Oral Care Systems

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  • US Patent:
    8354381, Jan 15, 2013
  • Filed:
    Mar 26, 2010
  • Appl. No.:
    12/732248
  • Inventors:
    Stephen R. Fahnestock - Wilmington DE, US
    Kari A. Fosser - Wilmington DE, US
    Hong Wang - Kennett Square PA, US
    Pierre E. Rouviere - Wilmington DE, US
    Tanja Maria Gruber - Media PA, US
    Douglas Robert Anton - Wilmington DE, US
  • Assignee:
    E I du Pont de Nemours and Company - Wilmington DE
  • International Classification:
    A61K 38/08
    A61C 17/00
    A61C 15/00
  • US Classification:
    514 216, 433 37, 4332171
  • Abstract:
    Oral care compositions, oral care systems, oral surface-binding peptides, and a method for applying particles to an oral surface are provided. The oral care system comprises at least one peptidic component comprising a first binding element having affinity for an oral surface and a second binding element having affinity for a ligand property of a particle.
  • Acid-Cleavable Linkers Exhibiting Altered Rates Of Acid Hydrolysis

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  • US Patent:
    8609621, Dec 17, 2013
  • Filed:
    Sep 7, 2011
  • Appl. No.:
    13/226610
  • Inventors:
    Laura A. Bedzyk - Odessa DE, US
    Stephen R. Fahnestock - Wilmington DE, US
    Tanja Maria Gruber - Media PA, US
    Daniel P. Okeefe - Ridley Park PA, US
    Pierre E. Rouviere - Wilmington DE, US
  • Assignee:
    E I du Pont de Nemours and Company - Wilmington DE
  • International Classification:
    A61K 38/08
    A61K 38/06
  • US Classification:
    514 217
  • Abstract:
    An acid-cleavable peptide linker comprising aspartic acid and proline residues is disclosed. The acid-cleavable peptide linker provides an altered sensitivity to acid-hydrolytic release of peptides of interest from fusion peptides of the formula PEP1-L-PEP2. The inventive linker, L, is described in various embodiments, each of which provides substantially more rapid acid-release of peptides of interest than does a single aspartic acid-proline pair. In an additional aspect, a method of increasing the stability of an acid cleavable linkage to acid hydrolysis is also provided.
  • Recombinant Peptide Production Using A Cross-Linkable Solubility Tag

    view source
  • US Patent:
    8617843, Dec 31, 2013
  • Filed:
    Apr 6, 2011
  • Appl. No.:
    13/080917
  • Inventors:
    Albert W. Alsop - Wilmington DE, US
    Qiong Cheng - Wilmington DE, US
    Linda Jane Solomon - Wilmington DE, US
    Stephen R. Fahnestock - Wilmington DE, US
    Tanja Maria Gruber - Media PA, US
    Pierre E. Rouviere - Wilmington DE, US
  • Assignee:
    E I du Pont de Nemours and Company - Wilmington DE
  • International Classification:
    C12P 21/06
    C07K 14/00
  • US Classification:
    435 691, 530350
  • Abstract:
    The invention relates to the recombinant expression of a peptide of interest in the form of a fusion protein comprising a solubility tag. The fusion protein comprises at least two portions separated by a cleavable peptide sequence wherein one portion is devoid of cysteine residues and the second portion comprises an effective number of cross-linkable cysteine residues. After cell lysis and isolation of the fusion protein, the fusion protein is subsequently cleaved into a mixture of first and second portions. Oxidative cross-linking is used to selectively precipitate one of the two portions to facilitate simple and effective separation of the peptide of interest.
  • Solubility Tags For The Expression And Purification Of Bioactive Peptides

    view source
  • US Patent:
    20090029412, Jan 29, 2009
  • Filed:
    Jul 25, 2007
  • Appl. No.:
    11/782836
  • Inventors:
    Qiong Cheng - Wilmington DE, US
    Linda Jane Decarolis - Wilmington DE, US
    Stephen R. Fahnestock - Wilmington DE, US
    Tanja Maria Gruber - Media PA, US
    Lisa Diane Reiss - Wilmington DE, US
  • International Classification:
    C12P 21/04
    C07K 7/00
    C12N 15/11
    C12N 15/00
    C12N 1/20
  • US Classification:
    435 681, 530324, 530325, 530350, 536 234, 4353201, 435243, 43525233, 435 697
  • Abstract:
    Peptide tags, referred to here as inclusion body tags, are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.

Resumes

Tanja Gruber Photo 1

Technical Leader - Microbiome

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Location:
Wilmington, DE
Industry:
Biotechnology
Work:
Dupont Nutrition & Health
Technical Leader - Microbiome

Dupont
Head of Biochemistry

Dupont Jan 2014 - Feb 2015
Science Manager

Dupont Feb 2013 - Dec 2013
Research Manager

Dupont May 2005 - Jan 2013
Principal Investigator
Education:
University of California, San Francisco
Penn State University
Doctorates, Doctor of Philosophy, Molecular Biology, Biochemistry, Microbiology
Johannes Kepler Universität Linz
Eth Zürich
Copenhagen International School
Rygaards International School
Skills:
Biochemistry
Biotechnology
Molecular Biology
Chemistry
R&D
Microbiology
Protein Chemistry
Metabolic Engineering
Science
Genetics
Life Sciences
Protein Purification
Chromatography
Biofuels
Organic Chemistry
Cell Culture
High Performance Liquid Chromatography
Hplc
Polymerase Chain Reaction
Research and Development
Languages:
French
Danish
English
German
Tanja Gruber Photo 2

Tanja Gruber

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Location:
Greater Philadelphia Area
Industry:
Chemicals

Amazon

Verkaufen Mit Freude Und Herz (German Edition)

Verkaufen mit Freude und Herz (German Edition)

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Ein Arbeits- und Lebenshandbuch, das aufmerksam machen möchte, mit welcher inneren Einstellung die Menschen an die Dinge in ihrem Leben herangehen. Es ist gedacht für Menschen, die mehr Bewusstsein entwickeln möchten, um (noch) mehr Freude in ihr Leben zu integrieren. Nicht nur Verkäufer im gesellsc...


Author
Tanja Gruber

Binding
Paperback

Pages
62

Publisher
BoD

ISBN #
3837021947

EAN Code
9783837021943

ISBN #
1

Der Mann Und Das Mädchen Vom Strich (German Edition)

Der Mann und Das Mädchen vom Strich (German Edition)

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Eine Spannende Geschichte über einen Arzt der sich in eine Prostituierte verschaut. Was wird seine Umgebung davon halten?


Author
Tanja Gruber

Binding
Paperback

Pages
38

Publisher
united p.c.

ISBN #
8490392056

EAN Code
9788490392058

ISBN #
2

Flickr

News

More Than 8 Percent Of Children With Cancer Have Genetic Predisposition

More than 8 Percent of Children with Cancer Have Genetic Predisposition

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  • he other authors areMichael Edmonson,Tanja Gruber,John Easton,Dale Hedges,Xiaotu Ma,Xin Zhou,Donald Yergeau,Mark Wilkinson,Bhavin Vadodaria,Xiang Chen,Rose McGee,Stacy Hines-Dowell,Regina Nuccio,Emily Quinn,Sheila Shurtleff,Michael Rusch,Aman Patel,Jared Becksfort, Shuoguo Wang,Am
  • Date: Nov 19, 2015
  • Category: Health
  • Source: Google

Googleplus

Tanja Gruber Photo 4

Tanja Gruber

Work:
Squarebox - Pomočnica direktorja (2011)
Education:
...previsoka...
Tanja Gruber Photo 5

Tanja Gruber

Tagline:
Hyperactive, open-minded, enthusiastic, cosmopolitan, creative, chocolate-lover & passionate cook.
Tanja Gruber Photo 6

Tanja Gruber

Tanja Gruber Photo 7

Tanja Gruber

Relationship:
Single
Tanja Gruber Photo 8

Tanja Gruber

Tanja Gruber Photo 9

Tanja Gruber

Tanja Gruber Photo 10

Tanja Gruber

Other Social Networks

Tanja Gruber Photo 11

Tanja Gruber Google+

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Network:
GooglePlus
Tanja Gruber has not filled out her profile yet. ... ,["105443835802340057246"," https://plus.google.com/105443... Gruber" ...

Facebook

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Tanja Gruber

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Youtube

Frontiers in Oncology - Tanja Gruber, MD, PhD

"Establishing Preeminence in Translational Pediatric Oncology: Bass Ce...

  • Duration:
    1h 3m 43s

Tanja Lasch - Die immer lacht (Live in der Ba...

Nur hier: Die meisten und besten Schlagervideos aller Zeiten! Von A, w...

  • Duration:
    3m 47s

Tanja Gruber Tik Tok video.

Thanks for watching this video. It will mean the world to me if you su...

  • Duration:
    11s

Tanja Lasch - Doch das Weinen hab' ich lngst ...

TANJA LASCH freut sich in diesem Herbst auf ihr ganz persnliches Schla...

  • Duration:
    3m 59s

Glutenfreies Krustenbrot

Mein Equipment und Bcher: *Buch Glutenfrei... Hausmannskost: Kochen u...

  • Duration:
    6m 26s

Max&Me Interview with Founder Tanja Gruber

A little Interview with the radiant & inspiring Tanja Gruber, Co-Found...

  • Duration:
    19m 7s

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