Vicki F Rosen

US Patent:

20030082233, May 1, 2003

Filed:

Dec 3, 2001

Appl. No.:

10/005228

Inventors:

Karen Lyons - Sherman Oaks CA, US
Vicki Rosen - Chestnut Hill MA, US
Aaron Daluiski - Las Vegas NV, US
Thomas Engstrand - Uppsala, SE
Matthew Bahamonde - Glen Cove NY, US
Laura Gamer - Chelmsford MA, US
Eric Agius - Toulouse, FR
Karen Cox - Saugus MA, US

International Classification:

A61K009/14
A61K039/395

US Classification:

424/484000, 424/146100

Abstract:

Methods and compositions are provided for the treatment of defects and disease involving osteoporosis, or osteopenic conditions. The methods comprises applying to the site of osteoporotic or osteopenic conditions a composition comprising aBMP-3 inhibitor or antagonist. The invention further provides methods and compositions for modulating or regulating the formation of bone utilizing BMP-3 compositions.

US Patent:

20060252724, Nov 9, 2006

Filed:

Jul 14, 2006

Appl. No.:

11/486532

Inventors:

Karen Lyons - Sherman Oaks CA, US
Vicki Rosen - Chestnut Hill MA, US
Aaron Daluiski - Las Vegas NV, US
Thomas Engstrand - Uppsala, SE
Matthew Bahamonde - Glen Cove NY, US
Laura Gamer - Chelmsford MA, US
Eric Agius - Toulouse, FR
Karen Cox - Saugus MA, US

International Classification:

A61K 48/00
A61K 39/395

US Classification:

514044000, 424145100

Abstract:

Methods and compositions are provided for the treatment of defects and disease involving osteoporosis or osteopenic conditions. The methods comprise applying to the site of osteoporotic or osteopenic conditions a composition comprising a BMP-3 inhibitor or antagonist. The invention further provides methods and compositions for modulating or regulating the formation of bone utlizing BMP-3 conditions.