Vijay P Singh

US Patent:

8529612, Sep 10, 2013

Filed:

Jun 24, 2009

Appl. No.:

12/490671

Inventors:

Vijay P. Singh - Pittsburgh PA, US

Assignee:

Mayo Foundation for Medical Education and Research - Rochester MN

International Classification:

A61F 7/00
A61F 7/12
A61B 19/00
A61M 29/00

US Classification:

607105, 607113, 128898, 60410105, 604113

Abstract:

Materials and methods for producing localized hypothermia in a patient (e. g. , for treatment of acute pancreatitis and pancreatic cancer).

US Patent:

20100160339, Jun 24, 2010

Filed:

May 13, 2008

Appl. No.:

12/600886

Inventors:

Mark A. McNiven - Rochester MN, US
Vijay P. Singh - Pittsburgh PA, US

Assignee:

MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN

International Classification:

A61K 31/496
A61P 1/18

US Classification:

51425218

Abstract:

This document provides methods and materials related to treating pancreatitis. For example, methods and materials relating to the use of a tyrosine kinase inhibitor to pancreatitis are provided.

US Patent:

20120046718, Feb 23, 2012

Filed:

Aug 18, 2011

Appl. No.:

13/212819

Inventors:

Vijay P. Singh - Pittsburgh PA, US

International Classification:

A61F 7/12
A61F 7/00

US Classification:

607105, 607 96

Abstract:

Materials and Methods for producing localized hypothermia in a patient for treatment of a weight disorder (e.g., obesity).

US Patent:

20120289588, Nov 15, 2012

Filed:

Apr 16, 2012

Appl. No.:

13/447850

Inventors:

Vijay Prem Singh - Pittsburgh PA, US

International Classification:

A61K 31/337
A61P 1/18

US Classification:

514449

Abstract:

The present invention relates to methods for treating pancreatitis and/or organ failure comprising administering, to a subject in need of such treatment, an effective amount of a lipase inhibitor. It is based, at least in part, on the discoveries that lipotoxicity contributes to inflammation, multisystem organ failure, necrotic pancreatic acinar cell death and in acute pancreatitis, and that inhibition of lipolysis was able to reduce indices associated with these conditions. Accordingly, in various embodiments, the present invention provides for methods and compositions for limiting lipotoxicity and thereby reducing the likelihood of poor outcomes associated with acute pancreatitis and other severe systemic conditions, especially in obese individuals.

US Patent:

20130338741, Dec 19, 2013

Filed:

Aug 21, 2013

Appl. No.:

13/972123

Inventors:

Vijay P. Singh - Pittsburgh PA, US

Assignee:

Mayo Foundation for Medical Education and Research - Rochester MN

International Classification:

A61F 7/12

US Classification:

607105

Abstract:

Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).

US Patent:

20210069013, Mar 11, 2021

Filed:

Oct 30, 2020

Appl. No.:

17/084669

Inventors:

- Rochester MN, US
Vijay P. Singh - Pittsburgh PA, US

International Classification:

A61F 7/12
A61M 25/10

Abstract:

Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).

US Patent:

20200385489, Dec 10, 2020

Filed:

Aug 25, 2020

Appl. No.:

17/002665

Inventors:

- Rochester MN, US
Vijay P. Singh - Scottsdale AZ, US

International Classification:

C07K 16/40
C07K 16/18
A61K 31/17
A61P 1/18
A61K 31/365

Abstract:

This document provides materials and methods for treating pancreatitis (e.g., severe acute pancreatitis), a complication associated with pancreatitis (e.g., organ failure), and/or an acute inflammatory condition in a mammal (e.g., inflammation from a burn or trauma). For example, methods and materials for using one or more colipase inhibitors to treat a mammal having pancreatitis (e.g., acute pancreatitis) are provided.

US Patent:

20180319894, Nov 8, 2018

Filed:

Nov 2, 2016

Appl. No.:

15/773450

Inventors:

- Rochester MN, US
Vijay P. Singh - Scottsdale AZ, US

Assignee:

Mayo Foundation for Medical Education and Research - Rochester MN

International Classification:

C07K 16/40
A61K 31/365
A61P 1/18

Abstract:

This document provides materials and methods for treating pancreatitis (e.g., severe acute pancreatitis), a complication associated with pancreatitis (e.g., organ failure), and/or an acute inflammatory condition in a mammal (e.g., inflammation from a burn or trauma). For example, methods and materials for using one or more colipase inhibitors to treat a mammal having pancreatitis (e.g., acute pancreatitis) are provided.