Brad O. Buckman - Oakland CA David D. Davey - El Sobrante CA William J. Guilford - San Leandro CA Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Gary B. Phillips - Pleasant Hill CA Shung C. Wu - El Cerrito CA Wei Xu - Richmond CA
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
William J. Guilford - Belmont CA Steven T. Sakata - San Diego CA Kenneth J. Shaw - San Rafael CA Shung Wu - Princeton NJ Wei Xu - Danville CA Zuchun Zhao - Richmond CA
This invention is directed to benzenamine derivatives of formula (I): wherein A, W, m, n, R , R , R , R , R and R are defined herein. These compounds are useful as anti-coagulants.
Benzamidine Derivatives And Their Use As Anti-Coagulants
Brad O. Buckman - Oakland CA David D. Davey - El Sobrante CA William J. Guilford - San Leandro CA Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Gary B. Phillips - Pleasant Hill CA Shung C. Wu - El Cerrito CA Wei Xu - Richmond CA
Assignee:
Berlex Laboratories, Inc. - Richmond CA
International Classification:
A61K 3153
US Classification:
514241, 544180, 544219
Abstract:
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Benzamidine Derivatives And Their Use As Anti-Coagulants
Brad O. Buckman - Oakland CA David D. Davey - El Sobrante CA William J. Guilford - San Leandro CA Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Gary B. Phillips - Pleasant Hill CA Shung C. Wu - El Cerrito CA Wei Xu - Richmond CA
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
N-Heterocyclic derivatives selected from the group consisting of the following formulae: where Z , Z , Z , R , R , R , R , R and R are described herein, are useful as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.
Piperazine Derivatives And Their Use As Anti-Inflammatory Agents
John G. Bauman - El Sobrante CA Brad O. Buckman - Oakland CA Ameen F. Ghannam - Briarcliff Manor NY Joseph E. Hesselgesser - San Francisco CA Richard Horuk - Lafayette CA Imadul Islam - Hercules CA Meina Liang - Danville CA Karen B. May - Napa CA Sean D. Monahan - Madison WI Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Kenneth J. Shaw - Brookside NJ Guo Ping Wei - San Ramon CA Wei Xu - Danville CA Zuchun Zhao - Richmond CA Wei Zheng - Blue Bell PA
Assignee:
Schering Aktiengesellschaft - Berlin
International Classification:
A61K 31495
US Classification:
51425501, 544387, 544388, 544391
Abstract:
This invention is directed to acyl piperazine derivatives, for example, of the following formula (1 ): wherein R , R , R , R , R , and R are descried herein. These derivatives are useful as anti-inflammatory agents. This invention is also directed to pharmacetutical compostions containing the derivatives, and methods of using the derivatives to treat inflammatory disorders in humans.
Piperazine Derivatives And Their Use As Anti-Inflammatory Agents
John G. Bauman - El Sobrante CA Brad O. Buckman - Oakland CA Ameen F. Ghannam - Briarcliff Manor NY Joseph E. Hesselgesser - San Francisco CA Richard Horuk - Lafayette CA Imadul Islam - Hercules CA Meina Liang - Danville CA Karen B. May - Napa CA Sean D. Monahan - Madison WI Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Kenneth J. Shaw - Brookside NJ Guo Ping Wei - San Ramon CA Wei Xu - Danville CA Zuchun Zhao - Richmond CA Wei Zheng - Blue Bell PA
Assignee:
Schering Aktiengesellschaft - Berlin
International Classification:
A61K 31496
US Classification:
51425213, 51425411, 544376
Abstract:
This invention is directed to acyl piperazine derivatives, for example, of the following formula (Ia): wherein R , R , R , R , R , and R are described herein. These derivatives are useful anti-inflammatory agents. This invention is also directed to pharmaceutical compositions containing the derivatives, and methods of using the derivatives to treat inflammatory disorders in humans.
Piperazine Derivatives And Their Use As Anti-Inflammatory Agents
John G. Bauman - El Sobrante CA Brad O. Buckman - Oakland CA Ameen F. Ghannam - Briarcliff Manor NY Joseph E. Hesselgesser - San Francisco CA Richard Horuk - Lafayette CA Imadul Islam - Hercules CA Meina Liang - Danville CA Karen B. May - Napa CA Sean D. Monahan - Madison WI Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Kenneth J. Shaw - Brookside NJ Guo Ping Wei - San Ramon CA Wei Xu - Danville CA Zuchun Zhao - Richmond CA Wei Zheng - Blue Bell PA
This invention is directed to acyl piperazine derivatives, for example, of the following formula (Ia): wherein R , R , R , R , R , and R are described herein. These derivatives are useful as anti-inflammatory agents. This invention is also directed to pharmaceutical compositions containing the derivatives, and methods of using the derivatives to treat inflammatory disorders in humans.
Jan 2010 to 2000 Project LeaderCH2M HILL Chicago, IL Apr 2009 to Jan 2010 Transportation ConsultantCH2M HILL Chicago, IL Aug 2008 to Apr 2009 Transportation Engineer
Education:
UNIVERSITY OF CHICAGO Chicago, IL Mar 2011 to 2000 Master of Business AdministrationOREGON STATE UNIVERSITY Corvallis, OR Jun 2008 M.S. in Civil EngineeringBEIJING INSTITUTE OF TECHNOLOGY Aug 2006 B.S. in Transportation Engineering
Skills:
LANGUAGE: excellent oral and written communications in English; native proficiency in Mandarin COMPUTER: Visual Basic, SAS, Splus, SPSS, MS Access, MS Word, MS Excel, PowerPoint, ArcGIS INTERESTS: basketball, beach volleyball, travelling
Wound Healing and Regenerative Medicine Laboratory
2009 to 2000 Postdoctoral Fellow
Education:
College of Veterinary Medicine, Michigan State University 2004 to 2009 Ph.D. in Pathobiology & Diagnostic InvestigationChinese Academy of Sciences 2001 to 2004 M.S. in Marine BiologyTianjin Agricultural College 1997 to 2001 B.S.
Dr. Xu graduated from the The Second Military Med Univ, Shanghai City, Shanghai, China in 1989. She works in Gaithersburg, MD and specializes in Family Medicine.
Kaiser Permanente Medical GroupKaiser Permanente Sacramento Medical Center 2345 Fair Oaks Blvd, Sacramento, CA 95825 9169735000 (phone), 9164806424 (fax)
Education:
Medical School Guangzhou Med Coll, Guangzhou City, Guangdong, China Graduated: 1982
Procedures:
Electrocardiogram (EKG or ECG) Hearing Evaluation Vaccine Administration
Bacharach Rehab MedicineBacharach Institute For Rehabilitation 61 W Jimmie Leeds Rd, Pomona, NJ 08240 6097485380 (phone), 6096528749 (fax)
Education:
Medical School The Second Military Med Univ, Shanghai City, Shanghai, China Graduated: 1985
Languages:
English Spanish
Description:
Dr. Xu graduated from the The Second Military Med Univ, Shanghai City, Shanghai, China in 1985. He works in Pomona, NJ and specializes in Physical Medicine & Rehabilitation. Dr. Xu is affiliated with Atlanticare Regional Medical Center and Shore Medical Center.
Hartford Orthopedic Medicine 100 Wl St STE 1B, Hartford, CT 06103 8602494466 (phone), 8602494469 (fax)
Education:
Medical School Capital Univ of Med Scis, Training Ctr of Gen Prac, Beijing City, China Graduated: 1995
Languages:
English Spanish
Description:
Dr. Xu graduated from the Capital Univ of Med Scis, Training Ctr of Gen Prac, Beijing City, China in 1995. He works in Hartford, CT and specializes in Physical Medicine & Rehabilitation.
Doctors On-Call 6010 Bay Pkwy STE 901, Brooklyn, NY 11204 7182382100 (phone), 7187480863 (fax)
Languages:
English
Description:
Ms. Xu works in Brooklyn, NY and specializes in Internal Medicine and Holistic Medicine. Ms. Xu is affiliated with Maimonides Medical Center, Mount Sinai Beth Israel Brooklyn Medical Center and New York Methodist Hospital.