Brad O. Buckman - Oakland CA David D. Davey - El Sobrante CA William J. Guilford - San Leandro CA Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Gary B. Phillips - Pleasant Hill CA Shung C. Wu - El Cerrito CA Wei Xu - Richmond CA
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
William J. Guilford - Belmont CA Steven T. Sakata - San Diego CA Kenneth J. Shaw - San Rafael CA Shung Wu - Princeton NJ Wei Xu - Danville CA Zuchun Zhao - Richmond CA
This invention is directed to benzenamine derivatives of formula (I): wherein A, W, m, n, R , R , R , R , R and R are defined herein. These compounds are useful as anti-coagulants.
Benzamidine Derivatives And Their Use As Anti-Coagulants
Brad O. Buckman - Oakland CA David D. Davey - El Sobrante CA William J. Guilford - San Leandro CA Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Gary B. Phillips - Pleasant Hill CA Shung C. Wu - El Cerrito CA Wei Xu - Richmond CA
Assignee:
Berlex Laboratories, Inc. - Richmond CA
International Classification:
A61K 3153
US Classification:
514241, 544180, 544219
Abstract:
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Benzamidine Derivatives And Their Use As Anti-Coagulants
Brad O. Buckman - Oakland CA David D. Davey - El Sobrante CA William J. Guilford - San Leandro CA Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Gary B. Phillips - Pleasant Hill CA Shung C. Wu - El Cerrito CA Wei Xu - Richmond CA
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
N-Heterocyclic derivatives selected from the group consisting of the following formulae: where Z , Z , Z , R , R , R , R , R and R are described herein, are useful as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.
Piperazine Derivatives And Their Use As Anti-Inflammatory Agents
John G. Bauman - El Sobrante CA Brad O. Buckman - Oakland CA Ameen F. Ghannam - Briarcliff Manor NY Joseph E. Hesselgesser - San Francisco CA Richard Horuk - Lafayette CA Imadul Islam - Hercules CA Meina Liang - Danville CA Karen B. May - Napa CA Sean D. Monahan - Madison WI Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Kenneth J. Shaw - Brookside NJ Guo Ping Wei - San Ramon CA Wei Xu - Danville CA Zuchun Zhao - Richmond CA Wei Zheng - Blue Bell PA
Assignee:
Schering Aktiengesellschaft - Berlin
International Classification:
A61K 31495
US Classification:
51425501, 544387, 544388, 544391
Abstract:
This invention is directed to acyl piperazine derivatives, for example, of the following formula (1 ): wherein R , R , R , R , R , and R are descried herein. These derivatives are useful as anti-inflammatory agents. This invention is also directed to pharmacetutical compostions containing the derivatives, and methods of using the derivatives to treat inflammatory disorders in humans.
Piperazine Derivatives And Their Use As Anti-Inflammatory Agents
John G. Bauman - El Sobrante CA Brad O. Buckman - Oakland CA Ameen F. Ghannam - Briarcliff Manor NY Joseph E. Hesselgesser - San Francisco CA Richard Horuk - Lafayette CA Imadul Islam - Hercules CA Meina Liang - Danville CA Karen B. May - Napa CA Sean D. Monahan - Madison WI Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Kenneth J. Shaw - Brookside NJ Guo Ping Wei - San Ramon CA Wei Xu - Danville CA Zuchun Zhao - Richmond CA Wei Zheng - Blue Bell PA
Assignee:
Schering Aktiengesellschaft - Berlin
International Classification:
A61K 31496
US Classification:
51425213, 51425411, 544376
Abstract:
This invention is directed to acyl piperazine derivatives, for example, of the following formula (Ia): wherein R , R , R , R , R , and R are described herein. These derivatives are useful anti-inflammatory agents. This invention is also directed to pharmaceutical compositions containing the derivatives, and methods of using the derivatives to treat inflammatory disorders in humans.
Piperazine Derivatives And Their Use As Anti-Inflammatory Agents
John G. Bauman - El Sobrante CA Brad O. Buckman - Oakland CA Ameen F. Ghannam - Briarcliff Manor NY Joseph E. Hesselgesser - San Francisco CA Richard Horuk - Lafayette CA Imadul Islam - Hercules CA Meina Liang - Danville CA Karen B. May - Napa CA Sean D. Monahan - Madison WI Michael M. Morrissey - Danville CA Howard P. Ng - El Sobrante CA Kenneth J. Shaw - Brookside NJ Guo Ping Wei - San Ramon CA Wei Xu - Danville CA Zuchun Zhao - Richmond CA Wei Zheng - Blue Bell PA
This invention is directed to acyl piperazine derivatives, for example, of the following formula (Ia): wherein R , R , R , R , R , and R are described herein. These derivatives are useful as anti-inflammatory agents. This invention is also directed to pharmaceutical compositions containing the derivatives, and methods of using the derivatives to treat inflammatory disorders in humans.
Jul 2012 to 2000 Senior Software EngineerAspenTechnology Inc Houston, TX Jul 2007 to Jul 2012 Senior Software EngineerInfologic Inc Shenandoah, TX May 2001 to Jul 2007 Software EngineerEwings Technologies, Inc Plano, TX Aug 2000 to May 2001 System engineerInfologic Inc
Dec 1999 to Aug 2000 Software EngineerComputalog Inc Fort Worth, TX Jul 1998 to Apr 1999 Senior ScientistTexas Christian University Fort Worth, TX Aug 1993 to Jul 1998 Teaching Assistant/Doctor candidateUniversity of Science and Technology of China Hefei Hefei, CN Jul 1987 to Aug 1993 Lecturer
Education:
University of Texas at Dallas Richardson Richardson, TX Aug 2000 Master of Science in Computer ScienceTexas Christian University Fort Worth, TX 1993 to 1998 PHD. in PhysicsJilin University Changchun China Aug 1987 Master of Science in PhysicsJilin University Changchun China Aug 1984 Bachelor of Science in Physics
Dr. Xu graduated from the The Second Military Med Univ, Shanghai City, Shanghai, China in 1989. She works in Gaithersburg, MD and specializes in Family Medicine.
Kaiser Permanente Medical GroupKaiser Permanente Sacramento Medical Center 2345 Fair Oaks Blvd, Sacramento, CA 95825 9169735000 (phone), 9164806424 (fax)
Education:
Medical School Guangzhou Med Coll, Guangzhou City, Guangdong, China Graduated: 1982
Procedures:
Electrocardiogram (EKG or ECG) Hearing Evaluation Vaccine Administration
Bacharach Rehab MedicineBacharach Institute For Rehabilitation 61 W Jimmie Leeds Rd, Pomona, NJ 08240 6097485380 (phone), 6096528749 (fax)
Education:
Medical School The Second Military Med Univ, Shanghai City, Shanghai, China Graduated: 1985
Languages:
English Spanish
Description:
Dr. Xu graduated from the The Second Military Med Univ, Shanghai City, Shanghai, China in 1985. He works in Pomona, NJ and specializes in Physical Medicine & Rehabilitation. Dr. Xu is affiliated with Atlanticare Regional Medical Center and Shore Medical Center.
Hartford Orthopedic Medicine 100 Wl St STE 1B, Hartford, CT 06103 8602494466 (phone), 8602494469 (fax)
Education:
Medical School Capital Univ of Med Scis, Training Ctr of Gen Prac, Beijing City, China Graduated: 1995
Languages:
English Spanish
Description:
Dr. Xu graduated from the Capital Univ of Med Scis, Training Ctr of Gen Prac, Beijing City, China in 1995. He works in Hartford, CT and specializes in Physical Medicine & Rehabilitation.
Doctors On-Call 6010 Bay Pkwy STE 901, Brooklyn, NY 11204 7182382100 (phone), 7187480863 (fax)
Languages:
English
Description:
Ms. Xu works in Brooklyn, NY and specializes in Internal Medicine and Holistic Medicine. Ms. Xu is affiliated with Maimonides Medical Center, Mount Sinai Beth Israel Brooklyn Medical Center and New York Methodist Hospital.