Weiqin Jiang from 14228 Hi Wood Dr, Rockville, MD 20850, age 57

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Location:

8 Glen Eyre Dr, Bridgewater, NJ 08807

Industry:

Pharmaceuticals

Work:

Fda
Chemistry and Manufacturing Control Reviewer
Johnson & Johnson
Senior Scientist

Education:

University of Chicago 1991 - 1996

Skills:

Chemistry

Substituted Tetracyclic Pyrroloquinolone Derivatives Useful As Phosphodiesterase Inhibitors
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US Patent:

6686349, Feb 3, 2004
Filed:

Nov 12, 2002
Appl. No.:

10/291978
Inventors:

Weiqin Jiang - Bridgewater NJ
Zhihua Sui - Flemington NJ
Assignee:

Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ
International Classification:

C07D47114
US Classification:

51421104, 514218, 5142295, 51425502, 540488, 540498, 544 99, 544343
Abstract:

The invention relates to novel tetracyclic pyrroloquinolone derivatives of the formula (I) or (II): wherein all variables are as herein defined, pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.

Substituted 2,4-Dihydro-Pyrrolo[3,4-B]Quinolin-9-One Derivatives Useful As Phosphodiesterase Inhibitors
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US Patent:

6800625, Oct 5, 2004
Filed:

Jun 17, 2003
Appl. No.:

10/463941
Inventors:

Weiqin Jiang - Raritan NJ
Zhihua Sui - Raritan NJ
Assignee:

Janssen Pharmaceutica N.V. - Beerse
International Classification:

A61K 314365
US Classification:

5142328, 51425212, 514292, 514293, 544126, 544336, 546 62, 546 63, 546 81, 546 82
Abstract:

The invention relates to novel 2,4-dihydro-pyrrolo[3,4-b]quinolin-9-one derivatives of the formula (I) and (IV): wherein all variables are as herein defined, pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.

Indole Derivatives Useful As Progesterone Receptor Modulators
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US Patent:

7183309, Feb 27, 2007
Filed:

Oct 21, 2005
Appl. No.:

11/255444
Inventors:

Weiqin Jiang - Raritan NJ, US
James J. Fiordeliso - Raritan NJ, US
Zhihua Sui - Raritan NJ, US
Assignee:

Janssen Pharmaceutica N.V. - Beerse
International Classification:

A61K 31/404
C07D 209/04
US Classification:

514418, 548452
Abstract:

The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical uses of these compounds are related to contraception, the treatment and/or prevention of secondary amenorrhea, dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minication of side effects of cyclid menstrual bleeding. Additional uses of the invention include stimulation of food intake.

Indole Derivatives As Selective Androgen Receptor Modulators (Sarms)
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US Patent:

7282507, Oct 16, 2007
Filed:

Apr 1, 2005
Appl. No.:

11/096664
Inventors:

James C. Lanter - Raritan NJ, US
Zhihua Sui - Raritan NJ, US
James J. Fiordeliso - Raritan NJ, US
Weiqin Jiang - Raritan NJ, US
Xuqing Zhang - Raritan NJ, US
Assignee:

Janssen Pharmaceutica N.V.
International Classification:

A61K 31/404
A61K 31/454
C07D 401/04
C07D 209/10
US Classification:

514323, 514414, 546187, 548466
Abstract:

The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Indole Derivatives As Selective Androgen Receptor Modulator (Sarms)
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US Patent:

7288553, Oct 30, 2007
Filed:

Apr 1, 2005
Appl. No.:

11/096673
Inventors:

James C. Lanter - Raritan NJ, US
Zhihua Sui - Raritan NJ, US
James J. Fiordeliso - Raritan NJ, US
Weiqin Jiang - Raritan NJ, US
Xuqing Zhang - Raritan NJ, US
Assignee:

Janssen Pharmaceutica N.V.
International Classification:

C07D 209/12
A61K 31/404
US Classification:

514339, 514415, 5462774, 548454, 548494, 548495, 548505, 548506, 548507, 548509
Abstract:

The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Indole Derivatives Useful As Progesterone Receptor Modulators
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US Patent:

7345084, Mar 18, 2008
Filed:

Jan 16, 2007
Appl. No.:

11/623376
Inventors:

Weiqin Jiang - Raritan NJ, US
James J. Fiordeliso - Raritan NJ, US
Zhihua Sui - Raritan NJ, US
Assignee:

Janssen Pharmaceutica N.V.
International Classification:

A61K 31/404
C07D 209/36
US Classification:

514418, 548484
Abstract:

The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical uses of these compounds are related to contraception, the treatment and/or prevention of secondary amenorrhea, dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minication of side effects of cyclid menstrual bleeding. Additional uses of the invention include stimulation of food intake.

Pyridine Imidazoles And Aza-Indoles As Progesterone Receptor Modulators
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US Patent:

7348432, Mar 25, 2008
Filed:

Oct 21, 2005
Appl. No.:

11/255361
Inventors:

Weiqin Jiang - Raritan NJ, US
James J. Fiordeliso - Raritan NJ, US
Zhihua Sui - Raritan NJ, US
Assignee:

Janssen Phamaceutica N.V. - Beerse
International Classification:

C07D 471/02
US Classification:

546121
Abstract:

The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more estrogen receptors. The compounds of the invention are useful in the treatment of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.

Indole Derivatives As Selective Androgen Receptor Modulators (Sarms)
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US Patent:

7427682, Sep 23, 2008
Filed:

Apr 1, 2005
Appl. No.:

11/096740
Inventors:

James C. Lanter - Raritan NJ, US
Zhihua Sui - Raritan NJ, US
James J. Fiordeliso - Raritan NJ, US
Weiqin Jiang - Raritan NJ, US
Xuqing Zhang - Raritan NJ, US
Assignee:

Janssen Pharmaceutica N.V.
International Classification:

C07D 471/02
C07D 491/02
C07D 498/02
C07D 513/02
C07D 515/02
US Classification:

546113
Abstract:

The present invention is directed to novel insole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Weiqin Jiang