Xiao F Lu

US Patent:

20210401436, Dec 30, 2021

Filed:

May 11, 2021

Appl. No.:

17/317869

Inventors:

- San Diego CA, US
Xiao Lu - San Diego CA, US

Assignee:

3DT Holdings, LLC - San Diego CA

International Classification:

A61B 17/11
A61L 27/58
A61L 27/26
A61L 27/36
A61L 27/54
A61M 1/36
A61L 27/50
A61F 2/00
A61F 2/06
A61L 27/56

Abstract:

Luminal grafts and methods of making and using the same. An exemplary luminal graft of the present disclosure is configured as a generally tubular element configured for nerve cells to grow therethrough and comprises at least one sheet of biological tissue having elastin fibers and collagen fibers, with the elastin fibers being a dominant component thereof; and a plurality of microchannels formed on a surface of the at least one sheet of biological tissue, each of the microchannels extending longitudinally between a first end and a second end of the at least one sheet of biological tissue and configured to provide intraluminal structural guidance to nerve cells proliferating therethrough.

US Patent:

20210369479, Dec 2, 2021

Filed:

Aug 17, 2021

Appl. No.:

17/404798

Inventors:

- San Diego CA, US
Xiao Lu - San Diego CA, US

Assignee:

3DT Holdings, LLC - San Diego CA

International Classification:

A61F 5/00

Abstract:

An intestinal device, or a non-constrictive cuff, is configured for placement around an intestine. In the closed position the non-constrictive cuff is configured to be around at least part or all of an intestine, wherein the non-constrictive cuff does not constrict the portion of the intestine when deployed. A first intestinal device can be deployed for placement around a portion of an intestine, wherein a proximal end of the first intestinal device is configured to longitudinally overlap a distal end of a second intestinal device when disposed around an intestine. A method of use for a first intestinal device or non-constrictive cuff is also disclosed.

US Patent:

20190305971, Oct 3, 2019

Filed:

Apr 3, 2018

Appl. No.:

15/944089

Inventors:

- San Diego CA, US
Xiao Lu - San Diego CA, US
Seung Hyuk Kang - San Diego CA, US

International Classification:

H04L 9/32
G11C 11/419
G11C 7/12

Abstract:

Physically unclonable function (PUF) memory employing static random access memory (SRAM) bit cells enhanced by stress for increased PUF output reproducibility. Stress voltage applied to SRAM bit cells enhances their skew so that the SRAM bit cells output their preferred initial state in subsequent PUF read operations regardless of process variation and other external environmental variations, such as temperature. The application of stress voltage on the SRAM bit cells in a PUF memory array takes advantage of the recognition of aging effect in transistors, where turning transistors on and off over time can increase threshold voltage resulting in lower drive current. Stress voltage can be applied to the SRAM bit cells to bias their threshold voltage to simulate this aging effect to enhance mismatch between transistors in the SRAM bit cell to more fully skew the SRAM bit cells for increased PUF output reproducibility with less susceptible to noise.

US Patent:

20190156895, May 23, 2019

Filed:

Jan 28, 2019

Appl. No.:

16/260026

Inventors:

- San Diego CA, US
Xiao LU - San Diego CA, US
Xiaonan CHEN - San Diego CA, US
Zhongze WANG - San Diego CA, US

International Classification:

G11C 16/10
G11C 17/14
H01L 27/112
H01L 29/792
G11C 16/04
G11C 17/18
G11C 17/16
H01L 29/423

Abstract:

A semiconductor device for a one-time programmable (OTP) memory according to some examples of the disclosure includes a gate, a dielectric region below the gate, a source terminal below the dielectric region and offset to one side, a drain terminal below the dielectric region and offset to an opposite side from the source terminal, a drain side charge trap in the dielectric region capable of programming the semiconductor device, and a source side charge trap in the dielectric region opposite the drain side charge trap and capable of programming the semiconductor device.

US Patent:

20190111181, Apr 18, 2019

Filed:

Oct 12, 2018

Appl. No.:

16/158910

Inventors:

Ghassan S. Kassab - La Jolla CA, US
Xiao Lu - San Diego CA, US

International Classification:

A61L 27/36

Abstract:

Methods for denucleation of biological tissue. A method of denucleating biological tissue can include exposing a target tissue to at least one hyperosmotic solution and at least one hypoosmotic solution in an alternating fashion, and then applying a glutaraldehyde solution to the target tissue to fix the extracellular matrix and cytoskeleton of the target tissue.

US Patent:

20180235634, Aug 23, 2018

Filed:

Apr 19, 2018

Appl. No.:

15/957699

Inventors:

- San Diego CA, US
Xiao Lu - San Diego CA, US

Assignee:

3DT Holdings, LLC - San Diego CA

International Classification:

A61B 17/11
A61L 27/50
A61L 27/58
A61L 27/26
A61L 27/36
A61L 27/54

Abstract:

Luminal grafts and methods of making and using the same. An exemplary luminal graft of the present disclosure is configured as a generally tubular element configured for nerve cells to grow therethrough and comprises at least one sheet of biological tissue having elastin fibers and collagen fibers, with the elastin fibers being a dominant component thereof; and a plurality of microchannels formed on a surface of the at least one sheet of biological tissue, each of the microchannels extending longitudinally between a first end and a second end of the at least one sheet of biological tissue and configured to provide intraluminal structural guidance to nerve cells proliferating therethrough.

US Patent:

20180200095, Jul 19, 2018

Filed:

Nov 21, 2017

Appl. No.:

15/819657

Inventors:

- San Diego CA, US
Xiao Lu - San Diego CA, US

Assignee:

3DT Holdings, LLC - San Diego CA

International Classification:

A61F 5/00

Abstract:

Intestinal devices and methods for facilitating weight loss. In at least one embodiment of a method of patient treatment of the present disclosure, the method comprises the step of positioning a device, that is configured to reduce or limit localized intestinal distension, around a portion of an intestine of a patient.

US Patent:

20170067879, Mar 9, 2017

Filed:

Mar 31, 2015

Appl. No.:

14/674638

Inventors:

- San Diego CA, US
Xiao Lu - San Diego CA, US

International Classification:

G01N 33/50

Abstract:

Methods to determine fluid filtration rates through mammalian luminal organs. In one method, the method comprises the steps of positioning a segment of a mammalian luminal organ within a device, the device configured to prevent axial flow conditions through a lumen of the segment from a first end of the segment to an opposite second end of the segment, obtaining a first segment measurement at a first time, obtaining a second segment measurement at a second time, and determining a rate of fluid filtration through a wall of the segment based upon a difference between the first segment measurement and the second segment measurement and a difference in time between the first time and the second time.