Xiaoling L Lu

age ~52

from Holmdel, NJ

Get Report

Also known as:

Connected to:

Processes For The Preparation Of Cis-4-[2-{[(3S,4R)-3-Fluorooxan-4-Yl]Amino}-8-(2,4,6-Trichloroanilino)-9H-Purin-9-Yl]-1-Methylcyclohexane-1-Carboxamide
view source
US Patent:

20190100522, Apr 4, 2019
Filed:

Oct 3, 2018
Appl. No.:

16/150345
Inventors:

- Summit NJ, US
Maryll Elaine GEHERTY - Pennington NJ, US
Matthew Michael KREILEIN - Hillsborough NJ, US
Xiaoling LU - Whippany NJ, US
Nanfei ZOU - Fanwood NJ, US
International Classification:

C07D 473/32
C07D 407/12
Abstract:

Provided herein are processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide, alternatively named (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide, or a salt, solvate, hydrate, or isotopologue thereof.

Solid Forms Of (1S,4S)-4-(2-(((3S,4R)-3-Fluorotetrahydro-2H-Pyran-4-Yl)Amino)-8-((2,4,6-Trichlorophenyl)Amino)-9H-Purin-9-Yl)-1-Methylcyclohexane-1-Carboxamide And Methods Of Their Use
view source
US Patent:

20180362529, Dec 20, 2018
Filed:

Jul 5, 2018
Appl. No.:

16/027503
Inventors:

- San Diego CA, US
Paul F. Fernandez - Roseland NJ, US
Tracy L. Gaebele - Green Brook NJ, US
Lianfeng Huang - Basking Ridge NJ, US
Matthew J. Jackson - Watchung NJ, US
Matthew M. Kreilein - Hillsborough NJ, US
Xiaoling Lu - Whippany NJ, US
Wenju Wu - Warren NJ, US
Jean Xu - Warren NJ, US
International Classification:

C07D 473/32
Abstract:

Provided herein are formulations, solid forms and methods of use relating to (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide.

Solid Forms Of (1S,4S)-4-(2-(((3S,4R)-3-Fluorotetrahydro-2H-Pyran-4-Yl)Amino)-8-((2,4,6-Trichlorophenyl)Amino)-9H-Purin-9-Yl)-1-Methylcyclohexane-1-Carboxamide And Methods Of Their Use
view source
US Patent:

20170283418, Oct 5, 2017
Filed:

Mar 31, 2017
Appl. No.:

15/475836
Inventors:

- San Diego CA, US
Paul F. Fernandez - Roseland NJ, US
Tracy L. Gaebele - Green Brook NJ, US
Lianfeng Huang - Basking Ridge NJ, US
Matthew J. Jackson - Watchung NJ, US
Matthew M. Kreilein - Hillsborough NJ, US
Xiaoling Lu - Whippany NJ, US
Wenju Wu - Warren NJ, US
Jean Xu - Warren NJ, US
International Classification:

C07D 473/32
Abstract:

Provided herein are formulations, solid forms and methods of use relating to (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4, 6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide.