Yongsheng Song from 114 Horizon View Ct, Madison, AL 35758, age 67, Phone: 2034301292

Us Patents

Thiolesters And Uses Thereof
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US Patent:

7625917, Dec 1, 2009
Filed:

Dec 16, 2003
Appl. No.:

10/738062
Inventors:

James A. Turpin - Frederick MD, US
Yongsheng Song - East Haven CT, US
Ettore Appella - Chevy Chase MD, US
John K. Inman - Bethesda MD, US
David G. Covell - Chevy Chase MD, US
William G. Rice - Madison CT, US
Anders Wallqvist - Frederick MD, US
Andrew Maynard - Wilmington DE, US
Mingjun Huang - Rockville MD, US
International Classification:

A61K 31/435
A61K 39/12
US Classification:

514277, 546 1, 546298, 435 5, 4242041, 514706
Abstract:

This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.

Isothiazoloquinolones And Related Compounds As Anti-Infective Agents
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US Patent:

8114888, Feb 14, 2012
Filed:

Feb 15, 2006
Appl. No.:

11/354521
Inventors:

Barton James Bradbury - Wallingford CT, US
Godwin Pais - Hamden CT, US
Qiuping Wang - Bethany CT, US
Milind Deshpande - Madison CT, US
Michael Pucci - Kensington CT, US
Yongsheng Song - Guilford CT, US
Edlaine Lucien - New Haven CT, US
Jason Allan Wiles - Hamden CT, US
Akihiro Hashimoto - Branford CT, US
Assignee:

Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:

A61K 31/4365
A61K 31/4375
C07D 491/14
US Classification:

514293, 546 83
Abstract:

The invention provides certain compounds and salts of Formula I and Formula II:.

8A,9-Dihydro-4Ah-Isothiazolo[5,4-B]Quinoline-3,4-Diones And Related Compounds As Anti-Infective Agents
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US Patent:

20060100215, May 11, 2006
Filed:

Nov 10, 2005
Appl. No.:

11/271556
Inventors:

Barton Bradbury - Wallingford CT, US
Milind Deshpande - Madison CT, US
Michael Pucci - Kensington CT, US
Qiuping Wang - Bethany CT, US
Jason Wiles - Hamden CT, US
Yongsheng Song - Guilford CT, US
Akihiro Hashimoto - Branford CT, US
Edlaine Lucien - New Haven CT, US
International Classification:

A61K 31/496
A61K 31/4745
C07D 498/02
US Classification:

514253030, 514291000, 544361000, 546083000
Abstract:

The invention provides compounds and salts of Formula I and Formula II: which possess antimicrobial activity. The invention also provides novel synthetic intermediates useful in making compounds of Formula I and Formula II. The variables n, m, p, R, R, A, R, R, R, R, R, Aand Rare defined herein. Certain compounds of Formula I and Formula II disclosed herein are potent and/or selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula I or Formula II and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula I or Formula II as the only active agent or may contain a combination of a compound of Formula I or Formula II and one or more other active agents. The invention also provides methods for treating microbial infections in eukaryotes.

Nad+-Dependent Dna Ligase Inhibitors
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US Patent:

20070082920, Apr 12, 2007
Filed:

Oct 6, 2005
Appl. No.:

11/244614
Inventors:

Yongsheng Song - Guilford CT, US
Yongchun Hou - Mentor OH, US
Sandeep Gupta - Concord OH, US
Aimee Reed - Willoughby OH, US
Debasis Ghosh - Perrysburg OH, US
International Classification:

A61K 31/519
C07D 487/02
US Classification:

514264100, 544250000, 544279000, 514267000
Abstract:

Disclosed herein are pyrido[2,3-d]pyrimidines having the structure

New Isothiazoloquinolones And Related Compounds As Anti-Infective Agents
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US Patent:

20120114601, May 10, 2012
Filed:

Jan 12, 2012
Appl. No.:

13/348703
Inventors:

Barton James Bradbury - Wallingford CT, US
Godwin Pais - Hamden CT, US
Quiping Wang - Bethany CT, US
Milind Deshpande - Madison CT, US
Michael Pucci - Kensington CT, US
Yongsheng Song - Guilford CT, US
Edlaine Lucien - New Haven CT, US
Jason Allan Wiles - Hamden CT, US
Akihiro Hashimoto - Branford CT, US
Assignee:

Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:

A61K 31/4745
A61K 31/4375
A61K 38/21
A61P 31/12
A61P 31/04
A61P 33/02
A61P 31/10
A61P 17/00
A61P 13/02
A61P 11/00
A61P 19/08
A61P 19/02
A61P 1/12
C07D 513/14
C07D 513/04
US Classification:

424 854, 546 83, 514293
Abstract:

The invention provides certain compounds and salts of Formula I and Formula II:which possess antimicrobial activity. The invention also provides novel synthetic intermediates useful in making compounds of Formula I and Formula II. The variables A, R, R, R, R, R, Aand Rare defined herein.Certain compounds of Formula I and Formula II disclosed herein are potent and selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula I or Formula II and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula I or Formula II as the only active agent or may contain a combination of a compound of Formula I or Formula II and one or more other active agents. The invention also provides methods for treating microbial infections in animals.

Method For Separating Components In Natural Oil
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US Patent:

20130121980, May 16, 2013
Filed:

Nov 15, 2011
Appl. No.:

13/297115
Inventors:

Yongsheng Song - Madison AL, US
Assignee:

Engineering Research Associates - Huntsville AL
International Classification:

A61K 8/92
A23D 9/02
C11D 7/60
C11D 13/12
A61K 8/97
A61K 8/35
US Classification:

424 941, 514772, 510505, 510459, 510463, 514784, 514785, 426417, 426601
Abstract:

Different components of natural oils are separated by forming solid complexes of components of the natural oil with a solvent, and then separating the solid complexes from the remaining liquids. The natural oil is cooled in the presence of a solvent, and at least one component of the oil forms the solid complex with the solvent. This solid complex is separated from the remaining liquid portion of the oil solution, which also contains the solvent. Additional options concentration steps can further concentrate the components left in the liquid phase.

Thiolesters And Uses Thereof
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US Patent:

6706729, Mar 16, 2004
Filed:

May 16, 2001
Appl. No.:

09/701451
Inventors:

James A. Turpin - Frederick MD
Yongsheng Song - East Haven CT
Ettore Appella - Chevy Chase MD
John K. Inman - Bethesda MD
David G. Covell - Chevy Chase MD
William G. Rice - Madison CT
Anders Wallqvist - Frederick MD
Andrew Maynard - Wilmington DE
Mingjun Huang - Rockville MD
Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:

A61K 3144
US Classification:

514298, 514354, 514355, 546298
Abstract:

This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.

Method For Separating Components In Natural Oil
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US Patent:

20150252287, Sep 10, 2015
Filed:

May 19, 2015
Appl. No.:

14/716282
Inventors:

- Huntsville AL, US
Yongsheng Song - Madison AL, US
International Classification:

C11B 3/00
A61K 47/22
A61K 47/10
A61K 47/28
A61K 47/12
B01D 11/04
A61K 47/44
C11D 7/24
C11D 7/26
A61K 47/08
A23D 9/02
A61K 47/06
C11D 7/44
Abstract:

Different components of natural oils are separated by forming solid complexes of components of the natural oil with a solvent, and then separating the solid complexes from the remaining liquids. The natural oil is cooled in the presence of a solvent, and at least one component of the oil forms the solid complex with the solvent. This solid complex is separated from the remaining liquid portion of the oil solution, which also contains the solvent. Additional options concentration steps can further concentrate the components left in the liquid phase.