Zhiren Xia from 1031 Delany Rd, Gurnee, IL 60031, age 63, Phone: 8476237684

Cyclobut-3-Ene-1,2,-Dione Inhibitors Of Polo-Like Kinases
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US Patent:

7956185, Jun 7, 2011
Filed:

May 24, 2007
Appl. No.:

11/753279
Inventors:

Robert B. Diebold - Waltham MA, US
Stevan W. Djuric - Libertyville IL, US
Vincent L. Giranda - Gurnee IL, US
Laura A. Hexamer - Grayslake IL, US
Nan-Horng Lin - Vernon Hills IL, US
Julie M. Miyashiro - Morton Grove IL, US
Thomas D. Penning - Elmhurst IL, US
Magdalena Przytulinska - Chicago IL, US
Thomas J. Sowin - Wadsworth IL, US
Gerard M. Sullivan - Lake Villa IL, US
Zhi-Fu Tao - Gurnee IL, US
Yunsong Tong - Libertyville IL, US
Anil Vasudevan - Union Grove WI, US
Le Wang - Vernon Hills IL, US
Keith W. Woods - Libertyville IL, US
Zhiren Xia - Gurnee IL, US
Henry Q. Zhang - Grayslake IL, US
Assignee:

Abbott Laboratories - Abbott Park IL
International Classification:

C07D 239/02
US Classification:

544297, 544162, 544211, 544402, 546159, 546246, 5462681, 548127, 548128, 548161, 548202, 548235, 548257, 5482622, 5483074, 5483461, 5483621, 5483731, 548470, 548503, 548517, 549 49, 549 80, 549471, 585 23
Abstract:

Compounds of formula (I).

Substituted Pyrrolo [1,2-A] Pyrazines As Calcium Channel Blockers
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US Patent:

8101614, Jan 24, 2012
Filed:

Jan 14, 2010
Appl. No.:

12/687465
Inventors:

Qingwei Zhang - Grayslake IL, US
Andrew O. Stewart - Libertyville IL, US
Zhiren Xia - Gurnee IL, US
Assignee:

Abbott Laboratories - Abbott Park IL
International Classification:

A61K 31/495
US Classification:

514249, 544350, 544383, 548484
Abstract:

The present application relates to calcium channel inhibitors comprising compounds of formula (I), formula (II), formula (III), or formula (IV),.

Substituted Piperidinylcarbonylbenzenesulfonamides As Calcium Channel Blockers
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US Patent:

8404719, Mar 26, 2013
Filed:

Dec 12, 2011
Appl. No.:

13/323029
Inventors:

Qingwei Zhang - Libertyville IL, US
Andrew O. Stewart - Libertyville IL, US
Zhiren Xia - Gurnee IL, US
Assignee:

AbbVie Inc. - North Chicago IL
International Classification:

A61K 31/445
US Classification:

514326, 546245, 548518
Abstract:

The present application relates to calcium channel inhibitors comprising compounds of formula (I), formula (II), formula (III), or formula (IV),.

Substituted Octahydropyrrolo[1,2-]Pyrazine Sulfonamides As Calcium Channel Blockers
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US Patent:

8648074, Feb 11, 2014
Filed:

Sep 26, 2012
Appl. No.:

13/627536
Inventors:

Sachin V. Patel - Round Lake IL, US
Richard J. Perner - Gurnee IL, US
John T. Randolph - Libertyville IL, US
Michael R. Schrimpf - Grayslake IL, US
Kevin R. Woller - Antioch IL, US
Zhiren Xia - Gurnee IL, US
Qingwei Zhang - Libertyville IL, US
Assignee:

AbbVie Inc. - North Chicago IL
International Classification:

A61K 31/495
US Classification:

514249, 544117, 544238, 544333, 544336, 544349, 5462681, 548202, 5483351, 548465, 549 59, 549469
Abstract:

The present application relates to: (a) compounds of Formula (I):.

Novel Amides That Activate Soluble Guanylate Cyclase
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US Patent:

20040121994, Jun 24, 2004
Filed:

Dec 20, 2002
Appl. No.:

10/325297
Inventors:

Steven Anderson - Aurora IL, US
Pramila Bhatia - Libertyville IL, US
Teodozyj Kolasa - Lake Villa IL, US
Masaki Nakane - Lake Bluff IL, US
Meena Patel - Green Oaks IL, US
Jeffrey Rohde - Evanston IL, US
Zhiren Xia - Wadsworth IL, US
Henry Zhang - Grayslake IL, US
International Classification:

A61K031/55
A61K031/541
A61K031/5377
A61K031/496
A61K031/495
A61K031/4545
A61K031/4439
US Classification:

514/183000, 514/217040, 514/227800, 514/235200, 514/253010, 514/317000, 514/318000, 514/210200, 514/341000, 540/597000, 544/059000, 544/060000, 544/124000, 544/360000, 546/193000, 546/268100, 548/950000, 548/954000
Abstract:

Compounds of formula (I) are useful for increasing cGMP levels in a mammal.

Tricyclic Pyrazole Kinase Inhibitors
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US Patent:

20060014816, Jan 19, 2006
Filed:

Mar 24, 2005
Appl. No.:

11/089473
Inventors:

Lee Arnold - Niantic CT, US
Jurgen Dinges - Grayslake IL, US
Richard Dixon - Jefferson MA, US
Stevan Djuric - Libertyville IL, US
Anna Ericsson - Schrewsbury MA, US
Kimba Fischer - Longmont CO, US
Alan Gasiecki - Vernon Hills IL, US
Vijaya Gracias - Lindenhurst IL, US
James Holms - Gurnee IL, US
Makoto Takeshita - Fukui, JP
Michael Michaelides - Libertyville IL, US
Melanie Muckey - Trevor WI, US
Paul Rafferty - Westborough MA, US
Douglas Steinman - Morton Grove IL, US
Carol Wada - Gurnee IL, US
Zhiren Xia - Gurnee IL, US
Henry Zhang - Grayslake IL, US
International Classification:

A61K 31/416
C07D 231/54
US Classification:

514406000, 548359100
Abstract:

Compounds of the present invention are useful for inhibiting protein tyrosine kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Substituted Octahydropyrrolo[1,2-A]Pyrazines As Calcium Channel Blockers
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US Patent:

20130085142, Apr 4, 2013
Filed:

Sep 26, 2012
Appl. No.:

13/627541
Inventors:

Sachin V. Patel - Round Lake IL, US
Richard J. Perner - Gurnee IL, US
John T. Randolph - Libertyville IL, US
Michael R. Schrimpf - Grayslake IL, US
Kevin R. Woller - Antioch IL, US
Zhiren Xia - Gurnee IL, US
Qingwei Zhang - Libertyville IL, US
Assignee:

ABBVIE INC. - North Chicago IL
International Classification:

C07D 487/04
US Classification:

5142332, 544349, 514249, 544295, 544116
Abstract:

The present application relates to: (a) compounds of Formula (I):and salts thereof, wherein Z, Z, Z, Z, R, R, and Rare as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use as calcium channel inhibitors.

Methods Of Treating Diabetic Neuropathy Using Benzenesulfonamides
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US Patent:

20130178477, Jul 11, 2013
Filed:

Jan 4, 2013
Appl. No.:

13/734385
Inventors:

Andrew O. Stewart - Libertyville IL, US
Zhiren Xia - Gurnee IL, US
Wolfram V. Nothaft - Riverwoods IL, US
Assignee:

AbbVie Inc. - North Chicago IL
International Classification:

A61K 31/4985
US Classification:

514249
Abstract:

This invention is directed to methods of treating diabetic neuropathy, particularly, diabetic peripheral neuropathy, in a patient in need of treatment thereof.

Zhiren Xia