Weixing L Luo

US Patent:

7138504, Nov 21, 2006

Filed:

Aug 11, 2005

Appl. No.:

11/201992

Inventors:

Vani B. Bodepudi - San Ramon CA, US
Amy P. Tsai - San Jose CA, US
Weixing Luo - Fremont CA, US
Rueyming Loor - Danville CA, US

Assignee:

Microgenics Corporation - Fremont CA

International Classification:

C07K 17/06
C07K 16/44
C12N 9/96
G01N 33/353
G01N 33/533

US Classification:

530403, 435 791, 435 792, 435188, 436518, 436544, 436546, 5303889, 5303898, 530406

Abstract:

The invention teaches derivatives of mycophenolic alcohol and methods of preparing immunogens and other conjugates useful in immunoassays for quantitatively measuring concentrations of mycophenolic acid (MPA) and/or active metabolites of MPA in patient specimens. Antibodies produced from the disclosed immunogens capable of binding to MPA with cross-reactivity of no more than 5% with inactive metabolites and commonly co-prescribed drugs. Further, immunoassays for measuring the concentration of MPA using such antibodies are taught.

US Patent:

20020160439, Oct 31, 2002

Filed:

Feb 27, 2001

Appl. No.:

09/794789

Inventors:

Lakshmi Anne - Hayward CA, US
Weixing Luo - Sunnyvale CA, US
Ker-kong Tung - Del Mar CA, US

Assignee:

Applied Biotech, Inc.

International Classification:

C12Q001/26
C12Q001/28

US Classification:

435/025000

Abstract:

A device and method to detect oxidant adulterants added to a sample to prevent detection of tetrahydrocannabinol and/or tetrahydrocannabinol metabolites. The device and method detect popularly available adulterants such as chromate and nitrite through their reaction with a chromogenic substrate for a peroxidase enzyme. The substrate may be applied to a pad. A change in color in the presence of the oxidant may be detected directly or indirectly. The device and method may be used to detect the presence of any oxidant adulterant and is not specific for only one or a few adulterants added to a urine sample submitted for drug testing.